CD Formulation services

Preformulation is an investigation of physical and chemical properties of a drug substance when used alone or combined with excipients. Early prediction of these properties will generate information useful to the formulator in developing stable and safe dosage forms with good bioavailability. At CD Formulation , our preformulation services are equipped with advanced instrumentation, and our research team not only have the expertise to handle the most complex formulations, but also have a depth of experience in the pharmaceutical industry and contract service organisations. CD Formulation can offer tailored and rational preformulation development. https://www.formulationbio.com/preformulation.html

CD Formulation can provide you with comprehensive services of API-excipient compatibility, our services can save both time and cost for you by assessing the risk of excipient interactions prior to formulation development. We test the materials that need in the formulation to determine their chemical and physical properties, and our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. Our API-Excipient Compatibility Services Obtain an in-depth understanding of physical or chemical API-excipient interactions. Support the selection of the most appropriate excipients in dosage form design. More at https://www.formulationbio.com/api-excipient-compatibility.html

CD Formulation can provide you with crystallinity determination services of active pharmaceutical ingredients, and our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. Our Methods for Crystallinity Determination Differential scanning calorimetry (DSC) FT-Raman spectrometry X-ray powder diffraction (XRPD) Near infrared spectroscopy (NIRS) More at https://www.formulationbio.com/crystallinity-determination.html

CD Formulation laboratories can test products of any scale, and we can provide comprehensive amorphous content determination for APIs according to related standards. Our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. More at https://www.formulationbio.com/amorphous-content-determination.html

CD Formulation laboratories can test products of any scale, and we can provide comprehensive hygroscopicity evaluation for APIs according to related standards. By determining whether APIs are sensitive to moisture, our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. Our Methods for Pharmaceutical Hygroscopicity Evaluation Gravimetric Sorption Analysis (GSA) Method Thermogravimetric Analysis (TA) More at https://www.formulationbio.com/hygroscopicity-evaluation.html

The particle size distribution of active ingredients and excipients is an important physical property of materials used to manufacture pharmaceutical products. The size, distribution and shape of the particles will affect the overall performance, stability and appearance of the final product. Therefore, particle size monitoring is essential for the entire drug development and manufacturing process. CD Formulation can provide comprehensive particle size analysis services of active ingredients and excipients, and our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues.

CD Formulation can provide you with LogP/LogD/pKa analysis services of APIs and inactive ingredients, and the pKa testing will be performed by our scientists through calculating the LogP or LogD values and measured in various pH values. It will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. More at https://www.formulationbio.com/logp-logd-pka-analysis.html

CD Formulation can provide you with dissolution profiles of active pharmaceutical ingredients in various solvents (including inorganic solvents with different pH values, organic solvents, simulated intestinal juice or gastric juice, and other solvents) according to your needs. In addition, our scientists specialize in providing solubility enhancement services through a variety of technologies and methods to minimize potential formulation and stability issues. Learn more at https://www.formulationbio.com/solubility-analysis.html Our Solubility Analysis Services Building a full range pH solubility profile Solubility in simulated gastrointestinal media Solubility improvement

CD Formulation can provide you with moisture content determination services of APIs and inactive ingredients, and our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. Learn more at https://www.formulationbio.com/moisture-content-determination.html Moisture Sources of Dosage Forms Bulk drug Manufacturing processes Inactive excipients Environmental conditions

Stability analysis is a very interesting field in pre-formulation research. Under the influence of various environmental factors (such as temperature, humidity, and light), the stability of active pharmaceutical ingredients (API) or the stability of pharmaceutical products is evaluated. This is helpful to study the internal stability of candidate drug molecules and obtain useful information, it is important to improve the integrity of pharmaceutical products and prevent changes in their physical, chemical and pharmacological properties. CD Formulation can provide you with stability analysis services of active ingredients and excipients, and our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. Learn more at https://www.formulationbio.com/stability-analysis.html