Charles River articles
The research summarized in this whitepaper provides a number of examples of how ALZET® pumps offer a superior pre-clinical drug dosing option for the delivery of a wide array of anti-cancer agents, including small molecules, immunotherapies, radiotherapies, combination treatments, and novel drug entities.
This whitepaper also explores how ALZET® pumps have been used to successfully test treatments for cancer-associated syndromes and treatment-related side effects.
As the complexity of advanced therapies continues to grow, more data is needed to establish a drug’s mode of action, efficacy, and long-term safety. It’s no wonder, then, that big data is fueling the drive for tomorrow’s therapies. However, most developers lack the in-house capabilities to produce it and/or the expertise to evaluate it.
Charles River has created a complete solution for clients whose programs depend on harnessing big data. Through a new partnership wi
Charles River is pleased to announce that the 5th Annual Viral Safety and Viral Clearance Summit will take place at the Hyatt Centric Fisherman`s Wharf in San Francisco, California on October 6 – 7, 2020.
More than 110 attendees and speakers joined us for last year`s event, which was held at the same venue. They represented various industries including regulatory, service, and technology, as well as representatives from FDA/CBER.
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Gene therapies involving recombinant adeno-associated viral (rAAV) vectors have been approved by FDA, EMA, and used in well over 100 clinical trials, demonstrating efficacy against many genetic diseases.
Improvements to AAV production and purification processes have focused on improving gene delivery
In order to meet the growing needs of the biologics testing industry, we`re excited to announce the expansion of our biologics site in Edinburgh. GMP testing services located in Tranent will be moving to Riccarton. The move will be fully complete by early 2020, and the new facility will have double the capacity to accommodate your testing needs.
All current sponsor methods and staff will be moving to the Riccarton facility, allowing us to provide all of the services that we curre
Gonadotropins regulate the development of ovarian follicles and stimulate the production of sperm, making them essential for reproduction. They are used therapeutically for assisted reproduction in humans and to induce ovulation and superovulation in various mammals. The potency of gonadotropins is required to be evaluated accurately to ensure there is consistency between batches to allow for subsequent reproducible treatments. These assays are typically performed in immature rats and ma
We`ve added over 125 new datasets to our Cancer Model Database. It provides access to a comprehensive collection of well-established tumor models for early-stage oncology research and increases their translational capabilities to the clinic.
The update adds new patient-derived xenograft (PDX) models for several cancer types, including anal, colon, kidney, renal, and leukemia. Additionally, this update provide