PREMIER Biosoft software

Mass Spectrometry

Model GlycanExplorer - A Software Tool for High Throughput Bio-Therapeutic Glycan Characterization

GlycanExplorer is a one-stop software solution for bio-therapeutic glycan characterization and quantification. With pre-loaded high-resolution accurate glycan spectral databases, the software allows you to identify probable glycan structures with unparalleled confidence. Extensive and comprehensive data organization along with interactive charts and plots facilitates achieving detailed profiling of glycan samples, which further helps in drawing meaningful biological conclusions.

Model SimGlycan - High Throughput Glycan & Glycopeptide Identification Tool using Mass Spectrometry Data

SimGlycan predicts structure of glycans from the MS/MS and multi-stage mass spectrometry (MSn) data. Furthermore, comprehensive support for resolving glycopeptides using LC-MS/MS glycopeptide data facilitates glycosylation studies. SimGlycan accepts experimental MS/MS data, matches them with its own database and finally generate a list of ranked candidate structures. Rank of each candidate indicates the proximity between the candidate structure and the experimental glycan. The rank is calculated based on a robust scoring mechanism that considers structure specific diagnostic ions observed in the experimental MS/MS spectra as well as the intensity of those observed peaks. SimGlycan also supports multistage mass spectrometry (MSn) data analysis for isomers differentiation.

Model SimLipid - High Throughput Lipid Identification and Quantification Software

High throughput lipid characterization tool for data from MSE, TripleTOF, MALDI TOF/TOF, LC-MS, LC-MS/MS systems. SimLipid® is a high throughput lipid identification and quantification software. It can process raw data from hundreds of LC-MS and MS/MS experimental runs for LC-peak detection, peak-picking, molecular feature finding and retention time alignment. The raw data or peaklists – dataset containing processed LC-MS data – can be subjected to MS and MS/MS database search for structural elucidation, even in batch mode. A proprietary scoring mechanism distinguishes isobaric candidate structures for each MS/MS scan.

Genomics

Model AlleleID - Comprehensive Desktop Tool

AlleleID® is a comprehensive desktop tool designed to address the challenges of bacterial identification, pathogen detection or species identification. With ClustalW multiple sequence alignment at its core, AlleleID® can be used to design species identification/cross species probes for microarrays or real time PCR including SYBR® Green, TaqMan® MGB, TaqMan® probes, Molecular Beacons and real time PCR primers. AlleleID® also offers support for designing microarray experiments for detecting alternative splicing events.

Model Beacon Designer - Design Specific and Efficient Oligos for All Major qPCR Assays

Design successful SYBR® Green, TaqMan®, HRMA Primers, MethyLight TaqMan®, LNA™ spiked TaqMan®, molecular beacons for both standard and NASBA® assays, Scorpions® and FRET assays by automatically interpreting BLAST results and avoiding template structures.