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MedChemExpressModel Moperone -1050-79-9

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Moperone (R 1658) is an antagonist for D2 dopamine receptor and D3 dopamine receptor, with IC50 of 1.0 nM and 1.0 nM[1].
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MCE products for research use only. We do not sell to patients.

Moperone

MCE China:Moperone

Brand:MedChemExpress (MCE)

Cat. No.HY-W777345

CAS:1050-79-9

Synonyms:Methylperidol; R 1658

Storage:Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Moperone (R 1658) is an antagonist for D2 dopamine receptor and D3 dopamine receptor, with IC50 of 1.0 nM and 1.0 nM.

IC50 & Target:D2 Receptor 1 nM (IC50) D3 Receptor 1 nM (IC50)

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References:

[1]. Burstein ES, et al., Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist. J Pharmacol Exp Ther. 2005 Dec;315(3):1278-87.  [Content Brief]

Brand introduction:
•   MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
•   More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
•   The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
•   Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
•   It has a professional experimental center and strict quality control and verification system;
•   Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
•   The biological activity of the products has been verified by the experiments of customers in various countries;
•   A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
•   Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
•   It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。