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MedChemExpressModel 1-Tetradecanol -112-72-1

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1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity[1].
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1-Tetradecanol

MCE China:1-Tetradecanol

Brand:MedChemExpress (MCE)

Cat. No.HY-W004294

CAS:112-72-1

Purity:99.34%

Storage:Store at room temperature 3 years In solvent -80°C 2 years -20°C 1 year

Shipping:Room temperature in continental US; may vary elsewhere.

Description:1-Tetradecanol is a straight-chain saturated fatty alcohol and antibacterial agent. 1-Tetradecanol can be isolated from Myristica fragrans. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity.

In Vitro:1-Tetradecanol (30-300 µM, 24 h) reduces IL‑8 production by AGS cells in response to H. pylori in a significant and dose‑dependent manner[2]. 1-Tetradecanol significantly reduces melanin in B16F10 cells dose-dependantly, without cell cytotoxicitiy[3].

IC50 & Target:IL-8

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References:

[1]. XiaoyeGeng, et al. Design and fabrication of reversible thermochromic microencapsulated phase change materials for thermal energy storage and its antibacterial activity. Energy. Volume 159, 15 September 2018, Pages 857-869.

[2]. Kim G, et al. Inhibitory effect of 1‑tetradecanol on Helicobacter pylori‑induced production of interleukin‑8 and vascular endothelial growth factor in gastric epithelial cells. Mol Med Rep. 2017 Dec;16(6):9573-9578.  [Content Brief]

[3]. Lee S Y, et al. Effects of 1-tetradecanol and β-sitosterol isolated from Dendropanax morbifera Lev. on skin whitening, moisturizing and preventing hair loss. Journal of the Society of Cosmetic Scientists of Korea, 2015, 41(1): 73-83.

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