MedChemExpress - Model Triphenyl phosphate -115-86-6
MCE products for research use only. We do not sell to patients.
Triphenyl phosphate
MCE China:Triphenyl phosphate
Brand:MedChemExpress (MCE)
Cat. No.HY-Y1322
CAS:115-86-6
Purity:98.0%
Storage:Store at room temperature 3 years In solvent -80°C 2 years -20°C 1 year
Shipping:Room temperature in continental US; may vary elsewhere.
Description:Triphenyl phosphate is an organic phosphate flame retardant. Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NFκB, leading to abnormal neurological behavior. Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NFκB), interleukin-6, and tumor necrosis factor α. Triphenyl phosphate can also cause allergic contact dermatitis.
IC50 & Target:IL-6
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References:
[1]. Xiaoxun Lu, et al. Triphenyl phosphate disrupts placental tryptophan metabolism by activating MAOA/ROS/NFκB. Sci Total Environ. 2023 Dec 15:904:166688. [Content Brief]
[2]. J G Camarasa, et al. Allergic contact dermatitis from triphenyl phosphate. Contact Dermatitis. 1992 Apr;26(4):264-5. [Content Brief]
Brand introduction:
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