MedChemExpress - Model Oxethazaine -126-27-2
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Oxethazaine
MCE China：Oxethazaine
Brand：MedChemExpress (MCE)
Cat. No.HY-B0955
CAS：126-27-2
Synonyms：Oxetacaine
Purity：99.94%
Storage：Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Shipping：Room temperature in continental US; may vary elsewhere.
Description：Oxethazaine (Oxetacaine), a precursor of phentermine?acidic, is an acid-resistent and orally active analgesic agent. Oxethazaine (Oxetacaine) has the potential for the relief of pain associated with?peptic ulcer disease?or?esophagitis.
In Vivo：Oxetacaine (intraperitoneal?injection; 5, 10, and 15 mg/kg; during days 4–11) doses induces significant conditioned place preference (CPP), and there are no differences among the groups. While its postive control group phentermine only 3 mg/kg causes significant CPP[1]..
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References：
[1]. SEIFTER J, ET AL. Oxethazaine and related congeners: a series of highly potent local anesthetics. Proc Soc Exp Biol Med. 1962 Mar;109:664-8. [Content Brief]
[2]. Soo-Yeun Lee, et al. The abuse potential of oxethazaine: Effects of oxethazaine on drug-seeking behavior and analysis of its metabolites in plasma and hair in animal models. Pharmacology, Biochemistry and Behavior [Content Brief]
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