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MedChemExpress - Model Iron(II) fumarate -141-01-5
MCE products for research use only. We do not sell to patients.
Iron(II) fumarate
MCE China:Iron(II) fumarate
Brand:MedChemExpress (MCE)
Cat. No.HY-B1651
CAS:141-01-5
Synonyms:Ferrous fumarate
Purity:95.0%
Storage:RT, stored under nitrogen In solvent -80°C 2 years -20°C 1 year
Shipping:Room temperature in continental US; may vary elsewhere.
Description:Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia.
In Vitro:Iron(II) fumarate (0.32%, 0.64%; 24 h) can restore the metabolic pathway disruption caused by cypermethrin, enhance the tolerance and cell viability of BmN cells to cypermethrin[1].
In Vivo:Iron(II) fumarate (0.32%, 0.64%; p.o.) can alleviate the damage of cypermethrin to silkworms[1]. Iron(II) fumarate (200-2000 mg/kg; 4 weeks; p.o.) can induce oxidative stress in the liver and colon of rats[2]. Iron(II) fumarate (3% of body weight; 100 mg ferrous fumarate (F) per kilogram feed (g/kg); twice daily; 6 weeks; p.o.) can alter the intestinal morphology and microbiota of Yellow River carp, increasing the diversity and richness of the microbiota[3].
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References:
[1]. Wang XY, et al. Fumarate mitigates disruption induced by fenpropathrin in the silkworm Bombyx mori (Lepidoptera): A metabolomics study. Insect Sci. 2023 Jun;30(3):789-802. [Content Brief]
[2]. Rimbach G, et al. Liver and colon oxidant status in growing rats fed increasing levels of dietary iron. J Trace Elem Med Biol. 1997 Jun;11(2):99-104. [Content Brief]
[3]. Ren HT, et al. Effect of Spirulina and Ferrous Fumarate on Intestinal Morphology and the Diversity of Gut Microbiota of Yellow River Carp. Biol Trace Elem Res. 2022 Sep;200(9):4142-4149. [Content Brief]
[4]. Zlotkin S, et al. Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods. Am J Clin Nutr. 2001 Dec;74(6):791-5. [Content Brief]
Brand introduction:
• MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
• More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
• The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
• Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
• It has a professional experimental center and strict quality control and verification system;
• Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
• The biological activity of the products has been verified by the experiments of customers in various countries;
• A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
• Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
• It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。
