MedChemExpress - Model 20a-Dihydroprogesterone -145-14-2
MCE products for research use only. We do not sell to patients.
20α-Dihydroprogesterone
MCE China:20α-Dihydroprogesterone
Brand:MedChemExpress (MCE)
Cat. No.HY-113062
CAS:145-14-2
Synonyms:20-OH-P
Purity:97.07%
Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping:Room temperature in continental US; may vary elsewhere.
Description:20α-Dihydroprogesterone is the metabolite of Progesterone (HY-N0437). 20α-Dihydroprogesterone inhibits cell proliferation and migration in breast tissue. 20α-Dihydroprogesterone inhibits aromatase in cell MCF-7aro with IC50 about 5 μM.
IC50 & Target:Human Endogenous Metabolite
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References:
[1]. Pasqualini JR, et al., The anti-aromatase effect of progesterone and of its natural metabolites 20alpha- and 5alpha-dihydroprogesterone in the MCF-7aro breast cancer cell line. Anticancer Res. 2008 Jul-Aug;28(4B):2129-33. [Content Brief]
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