MedChemExpress LLC (MCE)

MedChemExpressModel 20a-Dihydroprogesterone -145-14-2

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20α-Dihydroprogesterone is the metabolite of Progesterone (HY-N0437). 20α-Dihydroprogesterone inhibits cell proliferation and migration in breast tissue. 20α-Dihydroprogesterone inhibits aromatase in cell MCF-7aro with IC50 about 5 μM[1].
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20α-Dihydroprogesterone

MCE China:20α-Dihydroprogesterone

Brand:MedChemExpress (MCE)

Cat. No.HY-113062

CAS:145-14-2

Synonyms:20-OH-P

Purity:97.07%

Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Shipping:Room temperature in continental US; may vary elsewhere.

Description:20α-Dihydroprogesterone is the metabolite of Progesterone (HY-N0437). 20α-Dihydroprogesterone inhibits cell proliferation and migration in breast tissue. 20α-Dihydroprogesterone inhibits aromatase in cell MCF-7aro with IC50 about 5 μM.

IC50 & Target:Human Endogenous Metabolite

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References:

[1]. Pasqualini JR, et al., The anti-aromatase effect of progesterone and of its natural metabolites 20alpha- and 5alpha-dihydroprogesterone in the MCF-7aro breast cancer cell line. Anticancer Res. 2008 Jul-Aug;28(4B):2129-33.  [Content Brief]

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