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MedChemExpress - Model 1,4-Dimethoxybenzene -150-78-7
MCE products for research use only. We do not sell to patients.
1,4-Dimethoxybenzene
MCE China:1,4-Dimethoxybenzene
Brand:MedChemExpress (MCE)
Cat. No.HY-W015780
CAS:150-78-7
Purity:99.97%
Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping:Room temperature in continental US; may vary elsewhere.
Description:1,4-Dimethoxybenzene is an endogenous metabolite. 1,4-Dimethoxybenzene has an anti-anxiety effect, increasing atherogenic index (AI) levels in rabbits and inducing sedentary behavior. Sedentary behavior may increase blood cholesterol levels and disrupt blood lipids. 1,4-Dimethoxybenzene considers to be not clastogenic in the in vivo micronucleus test.
In Vivo:1,4-Dimethoxybenzene has anti-anxiety effects and increases AI levels, causing sedentary behavior. In rabbits model (0.6mg/dl, 1.8mg/dl; i.g.) sedentary behavior may increase blood cholesterol levels and disrupt blood lipids and could not improve lipid profile of lipid-lowering rabbits[1]. 1,4-Dimethoxybenzene (0, 2000 mg/kg; i.g.) considered to be not clastogenic in the in vivo micronucleus test[2].
IC50 & Target:Human Endogenous Metabolite
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References:
[2]. A.M. Api, et al. RIFM fragrance ingredient safety assessment, 1,2-dimethoxybenzene, CAS Registry Number 91-16-7. Food and Chemical Toxicology. 2019 Aug:130 Suppl 1:110618. [Content Brief]
Brand introduction:
• MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
• More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
• The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
• Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
• It has a professional experimental center and strict quality control and verification system;
• Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
• The biological activity of the products has been verified by the experiments of customers in various countries;
• A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
• Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
• It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。
