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MedChemExpressModel L-Carnosine -305-84-0

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L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging[1][2][3].
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L-Carnosine

MCE China:L-Carnosine

Brand:MedChemExpress (MCE)

Cat. No.HY-W013494

CAS:305-84-0

Purity:99.94%

Storage:Sealed storage, away from moisture and light Powder -80°C 2 years -20°C 1 year *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Shipping:Room temperature in continental US; may vary elsewhere.

Description:L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging.

In Vitro:L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging[1]. L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability[2].

IC50 & Target:Human Endogenous Metabolite

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References:

[1]. Hipkiss AR, et al. Would carnosine or a carnivorous diet help suppress aging and associated pathologies? Ann N Y Acad Sci. 2006 May;1067:369-74.  [Content Brief]

[2]. Guney Y, et al. Carnosine may reduce lung injury caused by radiation therapy. Med Hypotheses. 2006;66(5):957-9.  [Content Brief]

[3]. Jukić I, et al. Carnosine, small but mighty—prospect of use as functional ingredient for functional food formulation[J]. Antioxidants, 2021, 10(7): 1037.  [Content Brief]

Brand introduction:
•   MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
•   More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
•   The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
•   Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
•   It has a professional experimental center and strict quality control and verification system;
•   Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
•   The biological activity of the products has been verified by the experiments of customers in various countries;
•   A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
•   Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
•   It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。