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MedChemExpressModel Desacetylvinblastine -3352-69-0

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Desacetylvinblastine (4-Desacetylvinblastine) is the major metabolite of Vinblastine (HY-13780) and a cytotoxic agent. When used alone, desacetylvinblastine has poor anti-tumor effects, but it can exert significant anti-tumor activity when in the presence of specific conjugates[1].
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Desacetylvinblastine

MCE China:Desacetylvinblastine

Brand:MedChemExpress (MCE)

Cat. No.HY-133005

CAS:3352-69-0

Synonyms:4-Desacetylvinblastine; Desacetylvincaleukoblastine

Storage:Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Desacetylvinblastine (4-Desacetylvinblastine) is the major metabolite of Vinblastine (HY-13780) and a cytotoxic agent. When used alone, desacetylvinblastine has poor anti-tumor effects, but it can exert significant anti-tumor activity when in the presence of specific conjugates.

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References:

[1]. Brady SF, et al. Design and synthesis of a pro-drug of vinblastine targeted at treatment of prostate cancer with enhanced efficacy and reduced systemic toxicity. J Med Chem. 2002 Oct 10;45(21):4706-15.  [Content Brief]

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