MedChemExpress - Model ?-Tocopherol -54-28-4
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γ-Tocopherol
MCE China：γ-Tocopherol
Brand：MedChemExpress (MCE)
Cat. No.HY-N7148
CAS：54-28-4
Synonyms：D-γ-Tocopherol; (+)-γ-Tocopherol
Purity：99.63%
Storage：4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Shipping：Room temperature in continental US; may vary elsewhere.
Description：γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity.
In Vitro：γ-Tocopherol (D-γ-Tocopherol) is well absorbed and accumulates to a significant degree in some human tissues; it is metabolized, however, largely to 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman (gamma-CEHC), which is mainly excreted in the urine[1]. Plasma concentrations of γ-Tocopherol (D-γ-Tocopherol) are inversely associated with the incidence of cardiovascular disease and prostate cancer[1].
IC50 & Target：Cyclooxygenase Human Endogenous Metabolite
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References：
[1]. Q Jiang, et al. Gamma-Tocopherol, the Major Form of Vitamin E in the US Diet, Deserves More Attention. Am J Clin Nutr. 2001 Dec;74(6):714-22. [Content Brief]
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