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MedChemExpress - Model L-Asparagine -70-47-3
MCE products for research use only. We do not sell to patients.
L-Asparagine
MCE China:L-Asparagine
Brand:MedChemExpress (MCE)
Cat. No.HY-N0667
CAS:70-47-3
Synonyms:(-)-Asparagine; Asn; Asparamide
Purity:98.0%
Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Shipping:Room temperature in continental US; may vary elsewhere.
Description:L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity.
In Vitro:L-Asparagine (0.03 mM) can reverse the proliferation decline of six human cancer cells induced by ASNS siRNA knockdown[2]. L-Asparagine (10 mM, 4 h) can stimulate ODC activity and proliferation in IPEC-J2 cells[3].
IC50 & Target:Microbial Metabolite Human Endogenous Metabolite
Hot selling product:Acifran | D-Serine | Baricitinib (phosphate) | Butylated hydroxytoluene | Rebamipide | Panitumumab (anti-EGFR) | Gypenoside XLVI | Trifarotene | CJJ300 | Tolbutamide
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
References:
[1]. Chiu M, et al. Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia. Front Oncol. 2020 Jan 9;9:1480. [Content Brief]
[2]. Pathria G,et al. Translational reprogramming marks adaptation to asparagine restriction in cancer. Nat Cell Biol. 2019 Dec;21(12):1590-1603. [Content Brief]
[3]. Kandil HM, et al. L-glutamine and L-asparagine stimulate ODC activity and proliferation in a porcine jejunal enterocyte line. Am J Physiol. 1995 Oct;269(4 Pt 1):G591-9. [Content Brief]
Brand introduction:
• MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
• More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
• The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
• Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
• It has a professional experimental center and strict quality control and verification system;
• Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
• The biological activity of the products has been verified by the experiments of customers in various countries;
• A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
• Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
• It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。
