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MedChemExpressModel Amidase -9012-56-0

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Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes[1].
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Amidase

MCE China:Amidase

Brand:MedChemExpress (MCE)

Cat. No.HY-P2736

CAS:9012-56-0

Storage:Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes.

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References:

[1]. Weber BW, et al. The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning. J Biol Chem. 2013 Oct 4;288(40):28514-23.

[2]. Weber BW,et.al. The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning. J Biol Chem. 2013 Oct 4;288(40):28514-23.  [Content Brief]

[3]. Li W, et al. An Amidase Contributes to Full Virulence of Sclerotinia sclerotiorum. Int J Mol Sci. 2022 Sep 23;23(19):11207.  [Content Brief]

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