MedChemExpress - Model 2,4-D -94-75-7

2,4-D (2, 4-dichlorophenoxyacetic acid) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D can induce apoptosis. 2,4-D inhibits DNA and protein synthesis, thereby preventing normal plant growth and development[1][2][3].

2,4-D

MCE China：2,4-D

Brand：MedChemExpress (MCE)

Cat. No.HY-18572

CAS：94-75-7

Synonyms：2,4-Dichlorophenoxyacetic acid

Purity：99.88%

Storage：Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Shipping：Room temperature in continental US; may vary elsewhere.

Description：2,4-D (2, 4-dichlorophenoxyacetic acid) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D can induce apoptosis. 2,4-D inhibits DNA and protein synthesis, thereby preventing normal plant growth and development.

In Vitro：2, 4-D (25-200 μM, 72 h) inhibits the cell viability of A549 and WI38 with IC50 values of 126 ± 2.25 µM and 115 ± 4.39 µM, respectively. Induces apoptosis by influencing the cell cycle[2].

In Vivo：2,4-D (100 or 200 mg/kg, gavage for 30 days) has toxic effects on the reproductive system of male rats[3].

References：

[1]. Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57(2):302-10. [Content Brief]

[2]. Ganguli A, et al. 2, 4-Dichlorophenoxyacetic acid induced toxicity in lung cells by disruption of the tubulin-microtubule network. Toxicology Research, 2014, 3(2): 118-130.

[3]. Marouani N, et al. Effects of oral administration of 2,4-dichlorophenoxyacetic acid (2,4-D) on reproductive parameters in male Wistar rats. Environ Sci Pollut Res Int. 2017 Jan;24(1):519-526. [Content Brief]

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MedChemExpress - Model 2,4-D -94-75-7

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2,4-D