MedChemExpress - Model Phytochelatin 2 (PC2) -95014-75-8

Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis[1][2].

Phytochelatin 2 (PC2)

MCE China：Phytochelatin 2 (PC2)

Brand：MedChemExpress (MCE)

Cat. No.HY-P2512

CAS：95014-75-8

Storage：Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping：Room temperature in continental US; may vary elsewhere.

Description：Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis.

In Vitro：Phytochelatin synthase (PCS) uses the substrates glutathione (GSH, γGlu-Cys-Gly) and a cadmium (Cd)-bound GSH (Cd∙GS2) to produce the shortest phytochelatin product (PC2, (γGlu-Cys)2-Gly) through a ping-pong mechanism[3]. Phytochelatins and their glutathione (GSH) precursor are thiol-rich peptides that play an important role in heavy metal detoxification in plants and microorganisms[4].

Sequence：γGlu-Cys-γGlu-Cys-Gly

References：

[1]. phytochelatin, heavy, metals, chelate, homeostasis, glutathione, microorganisms, toxicity

[2]. Dennis KK, et al. Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental metals. Database (Oxford). 2019;2019:baz083. [Content Brief]

[3]. Chia JC, et al. Tentative identification of the second substrate binding site in Arabidopsis phytochelatin synthase. PLoS One. 2013;8(12):e82675. Published 2013 Dec 5. [Content Brief]

[4]. Jacquart A, et al. Cd2+ and Pb2+ complexation by glutathione and the phytochelatins. Chem Biol Interact. 2017;267:2-10. [Content Brief]

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MedChemExpress - Model Phytochelatin 2 (PC2) -95014-75-8

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Phytochelatin 2 (PC2)