RITAI - Automatic Fermenter Bioreactor

• Type : fermenter bioreactor industrial 500l fermentacion bioreactor automatic fermenter bioreactor bio fermenter bioreactor
• Material : Wetted parts are SS316L, and others are SS304.
• Production Capacity : 5L-300L
• Control Points : PH, DO, RPM, TEMP, FOAM,FEED, ETC
• Documents : DQ, IQ, OQ, PQ, FAT, SAT, Operation Manual, Drawing, etc.
• Applicable Industries : Biology, Biopharmaceutical, biotechnology Research, Bioengineering, Life Sciences, Cell and gene therapies
• Application : Antibodies, Vaccine, Bacteria, Enzyme, Fungi, Blood, Microbiology, etc
• Voltage : 110V, 220V, 240V, 380V, 400V
• Certification : ASME, PED 97/23/EC, NB, GB, ISO 9001:2008
• Stainless steel part finish : inside surface is 0.28-0.6μm by mechanical polishing, ( passivation or electropolish are optional) outside surface is 0.4-0.8μm by satin finish.
• Operating panel : English or Customized
• Pressure : Working pressure inside vessel:0.2mpa
• Design pressure inside vessel: 0.25mpa
• Working pressure inside jacket:0.3mpa
• Design pressure inside jacket: 0.35mpa
• Pressure can be also designed according to client’s detail requirement.
• Agitation : 
• 1.Fermentor use top servo motor or SEW decelerator, or bottom ABB motor
• 2.top mechanical agitator or bottom magnetic agitator l
• 3.speed range:50-400rpm
• 4.Fixed-Fluidized bed type agitator
• Equips of vessel : 
• 1. using alcohol flame inoculation
• 2. electrical heater
• 3. PH,DO, temp. sensor foam and level probe port, etc.
• Construction : Floor-top One fermenter vessel with one control system (siemens PLC and HMI)

Control Systems: Modern fermenters and bioreactors are equipped with advanced control systems, enabling precise regulation of parameters such as temperature, pH, dissolved oxygen, and agitation speed to optimize microbial growth and product formation.

Sterilization: Efficient sterilization methods, such as steam-in-place (SIP) systems or autoclaving, are integral to fermenters and bioreactors to maintain aseptic conditions and prevent contamination during the fermentation process.

Monitoring and Data Logging: Integrated sensors and monitoring devices provide real-time measurement and logging of critical process parameters, facilitating process optimization, data analysis, and quality control.

Industrial 500L Fermentation Bioreactor Considerations:

Scale-Up Capacity: A 500L fermentation bioreactor is designed for industrial-scale production, offering the capacity to accommodate large volumes of culture medium and high-density microbial cultures.

Material and Construction: Industrial bioreactors of this scale are typically constructed from high-grade stainless steel or other corrosion-resistant materials to ensure durability, hygiene, and compliance with regulatory standards for industrial bioprocessing.

Process Automation: Large-scale fermentation bioreactors often feature advanced automation and control systems, allowing for efficient operation, monitoring, and management of complex fermentation processes within industrial settings.

Customizability and Flexibility: Industrial bioreactors may offer customization options to meet specific process requirements and can be designed with flexibility to accommodate diverse fermentation applications and products.

In summary, the characteristics of fermenters and bioreactors, including the considerations for industrial 500L fermentation bioreactors, reflect the advanced technology and engineering required to support industrial-scale fermentation processes with a focus on efficiency, precision, and reliability.