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Onconova Xprt Equipment & Supplies

2 equipment items found
Onconova - Narazaciclib - Multi-kinase Inhibitor (ON 123300)

Onconova - Narazaciclib - Multi-kinase Inhibitor (ON 123300)

by:Traws Pharma   based inNewtown, PENNSYLVANIA (USA)
Narazaciclib (ON 123300) is a multi-kinase inhibitor targeting CDK 4/6 and additional kinases involved in tumor genesis, which the Company believes presents an innovative approach to treating advanced cancers including HR+ HER2- metastatic breast cancer that is, or has become, resistant to commercial CDK 4/6 inhibitors. Beyond metastatic breast cancer, the Company believes that narazaciclib (ON ...
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Onconova - Rigosertib - Small Molecule

Onconova - Rigosertib - Small Molecule

by:Traws Pharma   based inNewtown, PENNSYLVANIA (USA)
Rigosertib is a small molecule that inhibits multiple cellular signaling pathways driving cancer cell growth while having little effect on normal cells. In contrast to many kinase inhibitors, rigosertib does not interact at the ATP binding site, but acts via allosteric inhibition. Rigosertib has the potential to affect three critical pathways for cancer cell proliferation and survival: the ...
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