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Confocal NL
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Confocal - Model AION -Confocal Microscopy System

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The AION confocal microscopy system by Confocal NL represents the third generation of Line REscan confocal technology designed for high-contrast imaging of live cells and thick specimens. This system excels in long-term, low-signal imaging and features one of the most expansive fields of view available, achieving high sensitivity through camera-based detection combined with visible (VIS) and near-infrared (NIR) imaging capabilities. Its unique design leverages a 25 mm field of view with a motorized pinhole, offering unparalleled confocality and reduced phototoxicity, making it suitable for delicate live cell imaging. The system supports fast imaging with speeds over 1000 frames per second in fixed line mode and operates with wavelengths spanning 400 to 1100 nm. Adding to its versatility, AION can be integrated with existing widefield microscopes, enhancing them with advanced confocal capabilities. The system's robust design, combined with high detector sensitivity and low laser power requirements, makes it an ideal solution for imaging complex biological samples like organoids and zebrafish embryos.

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AION is the third generation of our fast Line REscan confocal technology. It provides high-contrast images from thicker specimens such as organoids, tissue samples, plant and animal model organisms. The gentle conditions for your live samples allow AION to excel in long-time-lapse experiments and imaging low-signal samples.

The combination of camera-based detection and a set of filters allows you to acquire your images in both visible (VIS) and near-infrared (NIR). This gives you an improved temporal resolution, high sensitivity and unprecedented signal-to-noise ratio. You get even faster imaging with cleaner results, thanks to additional motorized single-band emission filters.

Double the FOV - Double the observation

AION is a confocal system that allows a 25 mm field of view (FOV) with a motorized pinhole that ensures spot-on confocality every time. 

Our system uses a line illumination through a slit pinhole, instead of a point illumination found in point scanner confocal microscopes. This provides high temporal resolution while reducing phototoxicity. Since phototoxicity is one of the biggest challenges for researchers, this makes AION the perfect tool for live cell imaging.

You can also add AION to any widefield microscope. This will turn it into an advanced and fast scanning confocal imaging system.

Accelerate your research with the AION

A combination of low laser power requirements, high sensitivity of the detector and a novel optical design present in AION Line REscan enables imaging beyond 500μm of depth. This makes AION Line REscan confocal a perfect solution for live cell confocal microscopy of even thicker specimens like cleared tissue, whole zebrafish embryos, organoids and spheroids.

Explore the benefits

Our flagship AION has a switchable pinhole, ensuring flexibility, sensitivity and optimal confocality.

Nyquisting every objective and adding fast multicolour imaging over a large FOV gives raise to the most light-efficient confocal system on the market.