SIFT-MS Technology

1. Reagent ion generation and selection. The eight SIFT-MS reagent ions are formed by microwave discharge through moist or dry air at low pressure. One reagent ion is selected at any particular time using the first quadrupole mass filter.
2. Analyte ionization. The selected reagent ion is injected into the flow tube and excess energy is removed through collisions with the carrier gas. The sample is then introduced at a known flow rate and the reactive compounds it contains are ionized by the reagent ion to form well-characterized product ions.
3. Analyte detection and quantitation. Product ions and unreacted reagent ions are sampled into a second quadrupole mass spectrometer. Utilizing Syft’s compound library, the software instantaneously calculates each analyte’s absolute concentration.

SIFT-MS delivers real-time, chromatography-free direct analysis of compounds that traditionally require intensive sample preparation. No sample preparation is required for even complex matrices and high-humidity samples. SIFT-MS analyzes compounds that cannot be easily targeted by traditional chromatographic methods such as formaldehyde, hydrogen sulfide, ammonia, ethylene oxide, and nitrosamines.  It features unparalleled analytical flexibility in its ability to run chemically diverse samples and disparate methods back-to-back with a single configuration that does not require physical changeover routines.