Hjchem - Solid Phase Peptide Synthesis Vessel

1. Volume: 100ml,200ml, 500ml, 1L, 2L, 3L, 5L, 10L, 20L, 30L, 50L, 100L, for the laboratory scale, pilot plant and big industrial production scale. please refer our laboratory nutsche filter and industrial nutsche filter.

2. Vessel: Single wall, double wall or triple wall available

3. Working pressure: Full vacuum to 0.05Mpa

4. Working temperature: -80°C ~ +220°C

5. Filter device: PTFE, glass or stainless-steel sand core plate with pore size 0.1um to 200um and PTFE filter plate with filter cloth structure.

1.Resin Loading: The synthesis begins with loading the first amino acid onto the resin support. The amino acid is typically protected to prevent unwanted reactions.

2. Deprotection: The protective group on the amino acid is removed to expose its reactive amine group. This step prepares the amino acid for coupling with the next amino acid.

3. Amino Acid Coupling: The next amino acid, also protected, is activated using a coupling agent and then added to the reaction vessel. The activated amino acid reacts with the exposed amine group on the resin-bound amino acid, forming a peptide bond.

4. Repetition: The cycle of deprotection and coupling is repeated for each subsequent amino acid in the desired peptide sequence. The machine precisely controls each step to ensure high yield and purity.

5. Cleavage and Purification: Once the entire peptide sequence is synthesized, the peptide is cleaved from the resin support and deprotected. The crude peptide is then purified, typically using high-performance liquid chromatography(HPLC) or other purification methods.

For more information, please visit us:

Solid Phase Peptide Synthesis Vessel

https://njhjchem.com/product/glass-nutsche-filters/solid-phase-peptide-synthesis-vessel/