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Medgenome Xprt Industry Services
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Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
It is estimated that there are approximately 1010–1011 B cells in a human adult. A BCR is composed of two identical heavy chains generated by recombination of V, D and J segments and two identical light chains generated by recombination of V and J segments. Human BCRs undergo recombination at these variable regions, generating a large diverse receptor profile for each cell. Utilizing ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Single cell analysis has become a gold standard application in both basic as well as translational research. Several approaches are now available that capture the maximal transcript diversity in a given cell and allowing for multi-model analysis strategies to generate meaningful insights. MedGenome has adopted several commercially available platforms for single cell ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Whole Genome and Exome Sequencing applications have been widely accepted for use in genome wide association studies for complex diseases, variant calling to identify clinically actionable mutations and other specialized areas like identification of mutations that accumulate and give rise of tumor neo-antigens and shared antigens. At MedGenome, we routinely perform Whole Genome Sequencing and ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Epigenomic studies have a broad application in omic studies, allowing for deeper understanding of the underlying causes behind phenotypic changes in similar genotypes. Studying the DNA, histone modifications, DNA methylation and other chromatin components of interest, is a critical factor in epigenomic profiling. MedGenome has validated progressive applications for bulk and single cell ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
TCR profiling holds great potential not only for understanding the mechanisms of development of the normal immune response, but also in providing insights into disease mechanisms and development of new therapeutics and treatment modalities in infectious diseases, autoimmunity and in immuno-oncology. However, identification of all potential clonotypes in a diverse repertoire of TCRs requires ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Next generation sequencing enables gene expression analysis from normal and disease tissues with high-sensitivity. Profiling of coding and non-coding RNAs is important in revealing molecular mechanisms of development and disease. MedGenome has validated several options for gene expression profiling, accommodating a wide range of input from single-cell to thousands of cells and intact or degraded ...