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Version ASTRA -Luminary Software For Macromolecular and Nanoparticle Separation and Characterization

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ASTRA offers a suite of basic and advanced analyses, including customized reports and an optional 21 CFR Part 11 and EU Annex 11 compliant security and database package. It greatly simplifies MALS and DLS analysis, so you can quickly and accurately assess molar mass, size, conformation, conjugation and other essential physical parameters.

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Turn your data into results with the ultimate in light scattering software—ASTRA.

The most powerful and versatile software available for the characterization of macromolecules and nanoparticles via multi-angle and dynamic light scattering.

  • Maximize your productivity via ASTRA`s One-Click MW feature, automated multi-sequence processing and HPLC integration.
  • Take advantage of its integrated control of Agilent systems, or its support for Waters Empower sequences.

ASTRA Features and Capabilities

Browse these tabs to learn about the many capabilities and features in ASTRA which make it is the most powerful and versatile software available for the characterization of macromolecules and nanoparticles via multi-angle and dynamic light scattering.

ASTRA increases productivity for routine analyses

Running a SEC-MALS analyses has never been easier. ASTRA’s One-Click MW feature complete an entire method at the click of a button.

Click on Run Default and ASTRA will:

  • Synchronize data collection with your HPLC
  • Autoprocess data to determine MW and radius
  • Generate custom reports and graphs
  • Prepare for the next run

Method Builder

ASTRA`s Method Builder simplifies the specification of methods for the most common protein and polymer analyses, in three intuitive steps:

  • Choose your scientific application
  • Specify the instruments
  • Enter sample and run parameters

Then save the method, load the sample(s), click Run Default and return later to find out the MW results in the final report.

Freedom to Explore

With ASTRA, you are never locked in to default methods or standard procedures. You always* have access to each parameter and processing step to review, validate and improve.

*Except network accounts where access is limited under the 21 CFR Part 11 compliant Security Pack.

Ahead of the Curve

As you build expertise and confidence, and move on to complex analyses, ASTRA allows you to refine the results of automated processing with fine adjustments to peak selection, baseline specification, detector filtering and other settings.

A Complete SEC-MALS Solution

Full digital synchronization between your HPLC system, Wyatt detectors and ASTRA:
  • Minimizes user errors
  • Runs SEC-MALS from a single, familiar environment
  • Saves you time and money

ASTRA`s HPLC CONNECT module works with standard Agilent HPLC hardware including pumps, autosamplers, column ovens, UV/Vis detectors, and fraction collectors.

Integrated HPLC control with HPLC CONNECT

Let ASTRA take control of your HPLC stack for effortless synchronization between injections and data collection. ASTRA eliminates the need for separate HPLC and light scattering software. HPLC modules are listed together with Wyatt detectors in a common experiment configuration, and key parameters such as vial position, injection volume and flow rate are specified in ASTRA`s sequences.

Digital signal acquisition

HPLC CONNECT controls UV/VIS detectors directly within ASTRA. Set UV parameters and acquire all signals digitally, without any external cabling required. Select up to two UV channels for analysis – even post-collection.

HPLC CONNECT: Your Dashboard

The HPLC DASHBOARD application controls and monitors HPLC modules including pumps, column ovens, UV detectors and autosamplers, right from the desktop. Included at no additional cost with HPLC CONNECT.

Built from the ground up to handle large sets of data with ease, ASTRA has the tools you need to process and report on sequences containing many samples, including replicates. The "One-to-Many" batch processing feature lets you focus on your goals, and leave the drudgery to the computer.

EASI Table

Everything you need at a glance.

Quickly compare multiple data runs with the EASI Table feature to assess analyte stability and consistency. The table data can be exported in a variety of formats, or copied and pasted into your favorite word processing or spreadsheet software.

Fully customizable.

Specify which data should be displayed in EASI Table, as well as the format and precision used to display the values. Choose from percent or numerical uncertainties, or omit them entirely.

Sequence Processing

Collect data while you sleep.

Sequences are used to specify and control the automated collection of data as well as system functions. A sequence can be configured with the default method or a different method can be specified for each sample. Sequences also perform post-collection maintenance, such as running the COMET flow cell cleaner, switching the UV lamp off or switching the Orbit to solvent recycle mode.

In the Samples view, it is possible to modify sample parameters on-the-fly, adding samples, changing collection times, or skipping samples.

Let your computer do the work.

ASTRA allows you to process an experiment as you wish, then instruct the computer to apply the same settings and analysis steps on any number of additional data files. You can quickly and easily specify which elements of your `source` experiment should be incorporated in the target experiments.

Once the processing is finished, your resulting data files are fully analyzed and ready to be reviewed.