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47 applications found
Engineer antibodies that specifically kill cancer cells or equib cells with multiple functions, granting them the ability to invade human cancer-derived ...
ByTeselaGen Biotechnology, Inc. based in Portola Valley, CALIFORNIA (USA)
Natural killer (NK) cells have long been known to play a significant role in the body’s innate immune response. They were first described in the 1970s, but only in the last 15 years has significant progress been made in understanding the complexities and therapeutic potential these cells offer in helping fight cancer and other diseases. Today, we know that NK cells not only detect and identify malignant cancer ...
ByKiadis Pharma NV based in Amsterdam, NETHERLANDS
A non-invasive medical device, MarginProbe examines excised tissue during lumpectomy surgery and can detect the presence or absence of cancer cells on the margins. This provides vital, real time information to surgeons when it matters ...
ByDilon Technologies Inc. based in Newport News, VIRGINIA (USA)
Gastric cancer is a disease in which cancer cells form in the lining of the stomach. Almost all gastric cancers are adenocarcinomas, a cancer that begins in glandular tissue. Gastric cancer is often in an advanced stage when it is diagnosed. At this stage, it can often be treated, but rarely ...
ByAscelia Pharma AB based in Malmö, SWEDEN
Recovery of cervical cancer cells and isolation of circulating rare cells, detection and counting of bacteria recovered from food, beverage or cosmetics (flow cytometry, fluorescence microscopy), detection and analysis of recovered airborne particles (asbestos, AOX), ...
Byit4ip S.A. based in Louvain-la-Neuve, BELGIUM
One of the that cancer can be a serious disease is its ability to spread to other parts of the body beyond the location of the primary tumour. When cancer cells spread to distant lymph nodes, tissues or organs, it is called metastatic ...
ByAscelia Pharma AB based in Malmö, SWEDEN
Cancer is a group of diseases in which normal cells change and grow out of control. In breast cancer, the cancerous cells are usually cells of the lobules and ducts (ie, the glands that produce milk and the channels that carry milk to the nipple). Keep in mind that cancer, or carcinoma, of the breast can be broadly divided into two categories : ...
ByAurora Healthcare US Corp. based in Danvers, MASSACHUSETTS (USA)
IFN-α is a well-known therapeutic that was previously administered systemically for treatment of various cancers but it is currently rarely used because of its systemic toxicity. In the tumor microenvironment, IFN-α exerts its anti-tumor activity both directly by promoting cancer cell apoptosis and inhibiting vascularization and indirectly by restoring anti-tumor immune response. Temferon™ turns TEMs into a “Trojan Horse” to release ...
ByGenenta Science based in Milano, ITALY
The key FDA’s and EMA’s biosafety concerns (1,2) are the potential for cell based tumorigenicity, immunogenicity, infectious disease, and or genetic modification. Cellular therapies are aimed at specific disease types and to proliferate and differentiate into the desired cell type without causing unnecessary and potentially dangerous proliferation into cancer cells or unwanted immunogenicity causing damage in surrounding ...
ByAlcyomics Ltd. based in Newcastle Upon Tyne, UNITED KINGDOM
AlNovo is pioneering new therapeutic modalities based on our Novobinder Platform to harness the power of the human immune system to directly attack cancer ...
ByAinovo Biotech Inc. based in Sacramento, CALIFORNIA (USA)
This active molecular is a selective inhibitor of ALK(anaplastic lymphoma kinase)which is a target found in NSCLC (metastatic non-small cell lung cancer).https://www.bocsci.com/ceritinib-cas-1032900-25-6-item-462148.html ...
ByAlfa Chemistry based in New York, NEW YORK (USA)
IMMUNOSCORE® IC is intended for the detection of PD-L1 protein and the concomitant detection of CD8 + cells in Non-Small Cell Lung cancer (NSCLC) ...
ByVeracyte based in Marseille Cedex 9, FRANCE
Non-small cell lung cancer (NSCLC) is not a single disease, but a collection of cancer types whose pathology is classified by histology (cells) and molecular profiling (genetic and protein ...
ByBiocept based in San Diego, CALIFORNIA (USA)
The modular fashion with which Affilin® ligands can be fused together makes creating multi-specific binders an easy task. Combined with varying linker lengths, composition, and orientation, plus the optional addition of further accessory modules, our Navigo experts build the designed molecules as previously planned on the drawing ...
ByNavigo Proteins GmbH based in Halle, GERMANY
BOC Sciences is committed to supplying cost-effective products and services. We provide Peretinoin (Cas No:81485-25-8). More information, please visit the website: http://www.bocsci.com/peretinoin-cas-81485-25-8-item-84-305467.html ...
ByBOC Sciences based in Shirley, NEW YORK (USA)
The development of highly cytotoxic drugs is needed for the success of the treatment in tumor cells. Paradoxically, the high toxicity limits its efficacy and application in vivo, causing damage to non-target organs and severe secondary effects. The use of directed liposomes has allowed the advance of many cancer drugs to preclinical and clinical trials, reducing side effects, and increasing their therapeutic index at the same time. More than 15 cancer liposomed ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Data from examining the immune repertoire of cancer patients can be used to identify patterns associated with positive outcomes and monitor the progress of immunotherapies in clinical trials. Single cell immune sequencing technologies provide an even more granular view of individual T cell or B cell populations following immunotherapy, providing unprecedented detail for informing cancer ...
ByiRepertoire, Inc. based in Huntsville, ALABAMA (USA)
Peptides and peptidomimetics constitute excellent tumor-specific targeting moieties and can be coupled to therapeutic and diagnostic radioisotopes via a linker and a ...
By3B Pharmaceuticals GmbH based in Berlin, GERMANY
BOC Sciences is committed to supplying cost-effective products and services. We provide Halofuginone (Cas No:55837-20-2). More information, please visit the website: http://www.bocsci.com/halofuginone-cas-55837-20-2-item-84-71625.html ...
ByBOC Sciences based in Shirley, NEW YORK (USA)
Downregulating the immune response is necessary for the treatment of autoimmune diseases. In this aspect, the APO2L/TRAIL ligand is a key intermediate in immune cascades and is secreted in exosomes in natural conditions. Its alteration has been associated with rheumatoid arthritis. The administration of synthetic exosomes decorated with APO2L/TRAIL has been shown to be effective in reducing the hyperplasia and overall inflammation in this ...
ByNanovex Biotechnologies based in Llanera, SPAIN