Hematopoietic Cell Product Applications

3 applications found

Gene Therapy for Enduring Protection

We adapted an autologous ex-vivo gene therapy method to load the patient’s own TEMs precursors, that are hematopoietic stem and progenitor cells (HSPCs), with an immunotherapeutic transgene sequence. ...

ByGenenta Science based in Milano, ITALY

Target Enrichment with SRSLY and Twist Exome Panel

SRSLY NGS library preparation with twist exome panel enrichment for ctDNA SNP profiling. Cell-free DNA (cfDNA), found circulating in blood, originates predominantly from dying cells. In healthy individuals the vast majority of cfDNA derives from hematopoietic myeloid and lymph cells undergoing apoptosis. However, in individuals with cancer, a variable fraction of the cfDNA derives from tumor cells undergoing apoptosis and/or ...

ByClaret Bioscience based in Santa Cruz, CALIFORNIA (USA)

Safety & efficacy testing solutions for cellular therapies areas

The key FDA’s and EMA’s biosafety concerns (1,2) are the potential for cell based tumorigenicity, immunogenicity, infectious disease, and or genetic modification. Cellular therapies are aimed at specific disease types and to proliferate and differentiate into the desired cell type without causing unnecessary and potentially dangerous proliferation into cancer cells or unwanted immunogenicity causing damage in surrounding ...

ByAlcyomics Ltd. based in Newcastle Upon Tyne, UNITED KINGDOM

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