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29 applications found
Problems we solve: Pathogen contamination is often discovered post-packaging or distribution. Fermentation is poorly monitored in real-time. CIP hygiene lacks continuous microbial validation. Microbial shifts cause off-flavors or batch inconsistencies. Spoilage organisms can grow undetected between samples. Small sample sizes lead to non-representative microbial data. Lab testing is slow, costly, and ...
ByHolloid based in Wien, AUSTRIA
Problems we solve: Microbial contamination in bioreactors often goes undetected until product loss occurs. Not detecting low-viability cells reduces efficiency. Delayed lab results slow down decision-making in critical phases. Inability to track microbial subpopulations or phenotype shifts. High labor costs and limited skilled microscopy staff availability. Rare contaminants or early infections are hard to detect. Lack of data to optimize yield or identify process ...
ByHolloid based in Wien, AUSTRIA
Problems we solve: Pollution events go unnoticed between sparse lab tests. No continuous water quality monitoring in most systems. Tracking microplastics and sediments is extremely difficult. Biofouling is detected too late in cooling or filtration systems. Sampling is labor-intensive, error-prone, and expensive. Compliance relies on infrequent, static data points. Sudden microbial blooms or pollution runoff lack real-time ...
ByHolloid based in Wien, AUSTRIA
These 10 μm images (AFM topography and PiFM) are being acquired as azobenzene surface is being modified via UV light illumination over a 15-hour period. The PiFM image at 1100 cm-1 shows that as the surface roughens, the magnitude of this peak is growing smaller. At the same time, PiFM signal at 1693 cm-1 is getting stronger at some regions of the sample, especially at the lower regions of the surface ...
ByMolecular Vista based in San Jose, CALIFORNIA (USA)
In this example, Everaert et al. study the survival and homing capacity of BMSCs in a hindlimb ischemia mouse model in the presence or absence of immunosuppression treatment (CsA). Different injection routes are tested: intramuscular (IM) and intra-arterial ...
ByMauna Kea Technologies based in Paris, FRANCE
The longitudinal focal field of a tightly focused light via high NA (1.45 NA) objective lens is imaged via PiFM. The measured PiFM result agrees well (slight mismatch is observed due to the uncorrected nonlinearity of open-loop tip scanner) with the longitudinal field calculated from the dipole-dipole interaction between the polarized tip and the glass substrate. Scale bar: 1 micron. Image Courtesy: Ananth Tamma (PiFM image) and Fei Huang (field model), UC ...
ByMolecular Vista based in San Jose, CALIFORNIA (USA)
Incorporating nanocrystalline cellulose (NCC) into polyacrylonitrile (PAN) fiber changes the tensile property of PAN fiber. The goal is to identify the distribution of NCC on PAN fiber. The peaks associated with NCC are acquired by taking PiFM spectra of pure NCC sample. The NCC peaks compared to the glass substrate are clearly identified. These peaks are used to bring out the subtle features from the hyPIR image taken of the PAN-NCC sample. Note that the strengths of peaks are as such: strong (1034, 1059, 1273 ...
ByMolecular Vista based in San Jose, CALIFORNIA (USA)
Phaseform GmbH introduces an innovative approach to adaptive optics through its Deformable Phase Plate (DPP) technology, revolutionizing both microscopy and ophthalmology fields. The DPP provides dynamic aberration correction in microscopes, elevating image resolution and sharpness without the complexity of traditional adaptive optics systems. This refractive in-line technology seamlessly integrates into existing optical setups, offering a cost-effective solution that broadens the ...
ByPhaseform GmbH based in Freiburg, GERMANY
Identifying Components in Polymer Films via hyPIR Imaging. hyPIR (hyperspectral PiFM infrared) image consists of (n x n) pixels of PiFM spectrum. This is a hyPIRTM image (128 x 128 pixels) of 5 nm of PS homopolymer that is spin-coated onto a 2 nm thick PMMA homopolymer on top of silicon substrate. Due to the thin PS layer and its immiscibility with PMMA, PS has dewetted into nanoscale droplets. Up to three distinct region of a hyPIRTM image can be selected to average the spectra for each region. Up to three peaks ...
ByMolecular Vista based in San Jose, CALIFORNIA (USA)
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Every year over 400 million metric tons of plastic are produced globally for use in many applications, including construction, home appliances, medical instruments, and food packaging. Spectroscopy characterizes many important parameters associated with polymers and plastics ...
ByB&W Tek based in Plainsboro, DELAWARE (USA)
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Surface Enhanced Raman Spectroscopy or SERS is a specialized Raman technique that enhances the Raman scattering efficiency through the use of nanoparticles in solution or a treated surface. SERS improves the detection limit of Raman to the part per billion level and beyond for some ...
ByB&W Tek based in Plainsboro, DELAWARE (USA)
Use Cellvizio Lab to perform longitudinal studies on the peripheral nervous ...
ByMauna Kea Technologies based in Paris, FRANCE
In this example, the aggregation of magnetic nanoparticles labeled with DiR is monitored in real time. Tumor microvasculature is labeled using ...
ByMauna Kea Technologies based in Paris, FRANCE
Longitudinal imaging of pancreatic cancer. Monitor in a minimally invasive manner both tissue morphology and fibrosis (fluorescein) and cathepsin activity (Prosense® 680). A very thin probe (S 650) was used to monitor the pancreas of the same mouse over 9 months. ...
ByMauna Kea Technologies based in Paris, FRANCE
In archeological research, various specimens such as paintings, mummies, antique objects or fabrics are regularly investigated. Those samples are often unique and require specialized treatment when being analyzed. WITec imaging systems enable comprehensive sample analysis that provides a thorough understanding of the physical and chemical properties of archaeological samples. Confocal Raman imaging for example is a flexible, non-invasive and non-destructive tool for the chemical and molecular characterization of ...
ByWITec GmbH based in Ulm, GERMANY
From liquids to emulsions, solid samples, or coatings, etc. in the food technology diverse samples are analyzed on a regular basis. The flexible WITec imaging and analytical tools provide the opportunity to adjust the imaging technique to varying requirements. The samples can be comprehensively analyzed regarding their chemical and physical properties and depth profiles and 3D images can be generated to visualize the results in a clear and accessible ...
ByWITec GmbH based in Ulm, GERMANY
Stirrers, Autoclaves, Scales, Bain-marie, Biosafety and gas extraction cabinets, Centrifuges, Refrigerators and freezers, Distillers, Stoves and Incubators, Microscopes, Electrophoresis ...
ByBiocientífica S.A. based in Buenos Aires, ARGENTINA
Materials science is a diverse field including the development and testing of new substances, as well as the refinement of manufacturing processes and quality control for existing products. WITec imaging systems are particularly well-suited for comprehensive sample analyses in materials science and provide the opportunity to acquire a thorough knowledge of the sample surface morphology and chemical ...
ByWITec GmbH based in Ulm, GERMANY
Polymers have an important place in modern materials science. Due to the varying mechanical and chemical properties of polymers, they are used in almost every field of application and are important for the development of new materials with demanding requirements. WITec imaging systems enable comprehensive sample analysis that provides a thorough characterization of the physical and chemical properties of the polymers on the nanometer ...
ByWITec GmbH based in Ulm, GERMANY
Coatings and thin films are designed and developed to establish or alter various surface characteristics and in many cases the relationship between structure, morphology, and material properties is indispensable for the optimization of the material design. WITec imaging systems are particularly well-suited to contribute to the analysis of multi-component coating systems and thin films by visualizing the distribution of individual chemical components and the physical properties of different material ...
ByWITec GmbH based in Ulm, GERMANY