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Process Analysis System Product Applications In Switzerland
7 applications found
Understand, Optimize and Control Crystallization From Laboratory to Manufacturing Plant. It is challenging to design a crystallization process that will scale-up to reliably manufacture a consistent product meeting yield, purity and crystal size distribution specifications, and at the same time ensure efficient downstream processing in filtration, drying and product formulation ...
ByMettler - Toledo Int. Inc based in Greifensee, SWITZERLAND
Process Analytical Technology (PAT) has been implemented for years, particularly by the chemical industry for the control of chemical processes. More recently, PAT has become a cornerstone of the US Food and Drug Administration’s (US FDA) Quality by Design (QbD) initiative for both the design and control of quality processes. For this reason, the pharmaceutical industry is also active in utilizing PAT tools. PAT tools can be implemented in both the lab and the plant, with laboratory PAT focused more on the ...
ByMettler - Toledo Int. Inc based in Greifensee, SWITZERLAND
Monitoring chemical processes during manufacturing can be achieved with a mixture of in-line and at-line techniques, among them NIR and FTIR spectroscopy. Specac has a proven track record of supplying robust, rugged, reliable flow cells for in-line measurement. ...
BySpecac based in Orpington, UNITED KINGDOM
Optimize Multiphase Processes With In Situ Video and Real-Time Particle and Droplet Measurements. Particles and droplets are everywhere in the chemical, consumer products, pulp and paper, and petroleum industries. Particles grow, agglomerate, break, dissolve, and change shape - all of which can have an impact on process performance and product quality. To be successful, chemists and engineers must understand and optimize particle size distributions to control process efficiency such as stability, separations, or ...
ByMettler - Toledo Int. Inc based in Greifensee, SWITZERLAND
Process Development in the chemical industry requires a profound and comprehensive knowledge of the processes involved and is governed by a triangular relationship between 'Economy - Safety - ...
ByMettler - Toledo Int. Inc based in Greifensee, SWITZERLAND
Today, pharmaceutical and fine chemical companies face major challenges posed by globalization, environmental regulation, and shortened product life cycle that affect all aspects of their business. The research and development of an optimized chemical synthesis route must be carried out in less time and with less chemical waste to ensure a robust and economic process that can be efficiently scaled to manufacturing while meeting constraints related to product yield and purity, process and worker safety, and ...
ByMettler - Toledo Int. Inc based in Greifensee, SWITZERLAND
The particle size distribution is one of the most critical parameters in drug product quality. Real time understanding and control of particles ensures Quality by Design (QbD) in solid and liquid dosage formulation. FBRM and PVM Process Analytical Technologies (PAT) provide in-process real time measurements of particle dimension, particle shape, and particle count. FBRM and PVM are used to promote faster formulation development, improve process confidence, and control batch-to-batch ...
ByMettler - Toledo Int. Inc based in Greifensee, SWITZERLAND