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16,629 software items found
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The most recent version of NxClinical, the leading copy number variation (CNV) analysis software for clinical cytogenetics and molecular labs, now includes an integrated ACMG guidelines scoreboard ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The probe track view in NxClinical shows greater detail related to the supporting probes involved in this heteroUPD15 example. Enlarge the image to the right to reveal the heteroUPD15 visualized on both the top chromosome view (represented by the pink horizontal line) and the BAF plot for parental informative SNPs ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
Within the karyogram view, vertical bars are drawn within the AOH affected chromosome(s) to indicate parent-of-origin (pink=maternal; blue=paternal), and the same color indicators are displayed in the zygosity track. The image to the left displays a maternal inheritance represented by the pink probes on the BAF ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
In addition to using the scoreboard as a stand-alone guideline, this new feature can also be coupled with NxClinical's popular automated variant pre-classification decision tree to pre-classify events. This allows analysts to quickly sort through the events on the table and prioritize for ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
When analyzing SNP data, NxClinical users who deploy this new feature can now further investigate uniparental heterodisomy events within duos and trios with one simple click - saving them valuable time during the review process. ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
BioDiscovery has developed two algorithms for the detection of CNV and AOH events from NGS using its decades-long expertise in the area. One algorithm, the “Self-reference” algorithm, can be used for all WGS data regardless of sequencing depth. The second is the “Multi-Scale Reference” (MSR) algorithm that is applicable to all NGS data (WGS, WES, and Gene panels). The MSR ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
Getting CNV calls from Whole Exome Sequencing has been one of the most challenging efforts in the community. There have been numerous algorithms proposed but they suffer either from poor sensitivity or too many false-positive calls. The MSR algorithm has been able to offer the best balance of these competing measures, detecting small true-positives without generating many false-positives. The ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The MSR algorithm can be applied to any gene panel from single gene (e.g. DMD test) to large panels having thousands of gene. The image below is from the Illumina TruSightTM Oncology 500 (TSO500) panel showing a somatic cancer profile. The cytogenetic complexity of the tumor sample is clearly evident with a large copy number gain of 8p and loss of a large section of 13q. Aberrations associated ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The MSR algorithm can also be applied to detect CNVs from shallow sequencing, including very low-level mosaic events seen in NIPS or ctDNA samples. The image below shows a sample with trisomy 21 detected using 1x WGS. CNVs are an important contributor to disease and are required for accurate diagnosis. For clinical sequencing to be fully accepted as a replacement for microarrays and other ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
SoilStructure LIQUEFACTIONSPT, version 3 removes the pain of using calculators in analyzing potentially liquefiable sites. Spreadsheets are hard to preserve and it is time consuming to do all the columns and rows of calculations using in house tools. This liquefaction analysis software gives you pleasure and ease when factor of safety against liquefaction and seismic settlement. Liquefaction SPT ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
SoilStructure CANTILEVER SHORING, is a tool that analyses and designs cantilever shoring piles. We have added Australian Beams, British Beams and European Beams to the current North American (AISC) Beam Sections. This embedded retaining wall software only requires basic geometry and soils data. SoilStructure Software is pleased to announce the release of Cantilever Shoring Software. Others may ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
COMPLETE DESIGN OF MULTILEVEL ANCHORED OR BRACED SHORING WALLS (SI Units & English Units) – Up to 105 ft (32 m) deep. SoilStructure ABS, is for analyzing and designing multilevel tied back, tie rod, raker or strut shoring wall design. Spreadsheets are hard to preserve and it is time consuming to do all the stability and design checks using in house tools. This anchored or braced shoring ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
SoilStructure LATERAL FOUNDATION, version 2 analyses laterally loaded piles. Spreadsheets are hard to preserve and it is time consuming to do all the stability and design checks using in house tools. This Lateral Foundation software calculates the capacity of a single driven pile or a single drilled pier/auger cast pile subjected to: Lateral (Shear) load and, bending moment, free head or fixed ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
Drilled Pier is the most complete caisson design software currently on the market. It takes an hour to be at a productive rate and has both the SI & English unit systems. It is the only software that gives you lateral pressure and lateral resistance profile with drilled pier depth. Up until now, you needed one program for axial capacity, another for lateral load analysis and yet a third ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
Complete Analysis & Design Of Shallow Foundations: Bearing Capacity, Stability Analysis & Reinforcement Design.SoilStructure SHALLOW FOUNDATION, version 3 removes the pain of using calculators in the analysis and design of footings. Spreadsheets are hard to preserve and it is time consuming to do all the stability and reinforcement design using in house tools. This spread footing software ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
RAPID RETAIN – GEOTECHNICAL & STRUCTURAL EFFECTS ON CANTILEVER/RESTRAINED RETAINING WALLS – V4. (2018 IBC/ACI 318-19) – Accurate & Saves you time. SoilStructure RAPID RETAIN, version 4 is a tool for designing Abutment Wall, Wing Wall, Cantilever Retaining Wall & Basement Wall. It is time consuming to do all the stability and reinforcement design using in house ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
GRADE BEAM ANALYSIS – Analyses Grade Beams that are not soil supported which are subjected to Lateral Shear, Vertical Moment, Lateral Moment, Torsion and Axial Forces. V1. (ACI 318-14). SoilStructure GRADE BEAM, version 1 simplifies the calculations of grade beams spanning drilled pier supports. Spreadsheets are hard to preserve and it is time consuming to do the shear, moment, axial and ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
SoilStructure SETTLEMENT ANALYSIS software is for the purpose of trying to quickly assess effects of soil consolidation on structures. After more than 3 months of research, review of more than 21 books and months of programming subroutines, SoilStructure Software is pleased to announce the release of SETTLEMENT ANALYSIS Software, New version ...
by:SoilStructure Software, Inc.  based inAnaheim, CALIFORNIA (USA)
SoilStructure RAPID RETAIN, version 3 is a tool for designing Abutment Wall, Wing Wall, Cantilever Retaining Wall & Basement Wall. It is time consuming to do all the stability and reinforcement design using in house tools. The program can also analyze Fence Property Line Walls. It currently only uses the English unit system. Rapid Retan also complies with the requirements of ACI 318-14 and ...
by:Pixxel  based inEl Segundo, ALABAMA (USA)
Aurora, developed by Pixxel, is an Earth Observation Studio designed to transform satellite imagery into actionable insights, creating a seamless analysis experience. By leveraging remote sensing technology, it aims to make Earth Observation data accessible to a wide range of users, enabling them to spectrally fingerprint the Earth in new ways. The platform provides access to an extensive archive ...