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16,614 software items found
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
High-quality detection of CNV from NGS data has been a challenge for many years. BioDiscovery has perfected algorithms for the detection of CNV and AOH from almost all NGS ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
Bionano's NxClinicalTM Software is the leading copy number variation (CNV) analysis software solution for cytogenetics and molecular laboratories. The latest software (v6.2) release adds three measures of genomic instability for homologous recombination repair deficiency (HRD) in solid tumors: Loss of heterozygosity (LOH). Telomeric Allelic Imbalance (TAI). Large-Scale State Transitions (LST). ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The most recent version of NxClinical, the leading copy number variation (CNV) analysis software for clinical cytogenetics and molecular labs, now includes an integrated ACMG guidelines scoreboard ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The probe track view in NxClinical shows greater detail related to the supporting probes involved in this heteroUPD15 example. Enlarge the image to the right to reveal the heteroUPD15 visualized on both the top chromosome view (represented by the pink horizontal line) and the BAF plot for parental informative SNPs ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
Within the karyogram view, vertical bars are drawn within the AOH affected chromosome(s) to indicate parent-of-origin (pink=maternal; blue=paternal), and the same color indicators are displayed in the zygosity track. The image to the left displays a maternal inheritance represented by the pink probes on the BAF ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
In addition to using the scoreboard as a stand-alone guideline, this new feature can also be coupled with NxClinical's popular automated variant pre-classification decision tree to pre-classify events. This allows analysts to quickly sort through the events on the table and prioritize for ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
When analyzing SNP data, NxClinical users who deploy this new feature can now further investigate uniparental heterodisomy events within duos and trios with one simple click - saving them valuable time during the review process. ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
BioDiscovery has developed two algorithms for the detection of CNV and AOH events from NGS using its decades-long expertise in the area. One algorithm, the “Self-reference” algorithm, can be used for all WGS data regardless of sequencing depth. The second is the “Multi-Scale Reference” (MSR) algorithm that is applicable to all NGS data (WGS, WES, and Gene panels). The MSR ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
Getting CNV calls from Whole Exome Sequencing has been one of the most challenging efforts in the community. There have been numerous algorithms proposed but they suffer either from poor sensitivity or too many false-positive calls. The MSR algorithm has been able to offer the best balance of these competing measures, detecting small true-positives without generating many false-positives. The ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The MSR algorithm can be applied to any gene panel from single gene (e.g. DMD test) to large panels having thousands of gene. The image below is from the Illumina TruSightTM Oncology 500 (TSO500) panel showing a somatic cancer profile. The cytogenetic complexity of the tumor sample is clearly evident with a large copy number gain of 8p and loss of a large section of 13q. Aberrations associated ...
by:BioDiscovery, A Bionano Genomics Company  based inEl Segundo, CALIFORNIA (USA)
The MSR algorithm can also be applied to detect CNVs from shallow sequencing, including very low-level mosaic events seen in NIPS or ctDNA samples. The image below shows a sample with trisomy 21 detected using 1x WGS. CNVs are an important contributor to disease and are required for accurate diagnosis. For clinical sequencing to be fully accepted as a replacement for microarrays and other ...
Manufactured by:Logic Beach Inc  based inLa Mesa, CALIFORNIA (USA)
HyperWare (HW) is a powerful multi-purpose software package for use in concert with the HyperLogger, ModuLogger, and ModuLogger Mini Portable Data Logging Systems. Within the HyperWare software, all of the functions required for configuration and use of the Logic Beach data loggers are ...
Manufactured by:Logic Beach Inc  based inLa Mesa, CALIFORNIA (USA)
HyperWare-II (HW-II) is a powerful multi-purpose software package for use with the new Logic Beach IntelliLogger data logger series. HyperWare-II is the next generation icon-based data logging software built upon the original industry-preferred HyperWare program and contains all the functions required for configuration and use of the IntelliLogger. With HW-II you can graphically build data ...
Manufactured by:Radlink, Inc.  based inEl Segundo, CALIFORNIA (USA)
Surgeon’s Checklist Hip provides preoperative case planning, intraoperative imaging analysis and surgical guidance tools to evaluate alignment and verify component positioning during primary Total Hip Arthroplasty and Revision ...
Manufactured by:Radlink, Inc.  based inEl Segundo, CALIFORNIA (USA)
Surgeon’s Checklist PAO provides a dedicated set of tools for hip preservation specialists to analyze x-ray images and automatically determine patient-specific measurements during Periacetabular Osteotomy. When treating patients with complex hip disorders, such as hip dysplasia, AI image analysis software, real-time guidance and data allows for intraoperative adjustments in the operating ...
Manufactured by:Radlink, Inc.  based inEl Segundo, CALIFORNIA (USA)
Surgeon’s Checklist FAI platform, powered by AI image analysis, provides a dedicated set of tools that guide surgeons intraoperatively during Femoral Acetabular Impingement. When treating patients for hip arthroscopy and sports medicine, computer vision technology automatically detects the bony landmarks and provides non-invasive scope guidance to accurately repair damage to the ...
Manufactured by:Radlink, Inc.  based inEl Segundo, CALIFORNIA (USA)
Surgeon’s Checklist® TRAUMA provides an efficient and accurate imaging workflow and dedicated set of alignment tools that allow surgeons to accurately evaluate and recreate a patient’s anatomy during a full range of complex trauma ...
Manufactured by:Radlink, Inc.  based inEl Segundo, CALIFORNIA (USA)
OrthoPlan 2.0 Digital Templating software is a streamlined surgical planning tool that allows surgeons to create a personalized patient plan to prepare for each case preoperatively. Preop planning creates a roadmap for surgery that can be seamlessly integrated to the OR and verified using Surgeon’s Checklist® software for surgical guidance and intraoperative ...
Manufactured by:CRISPR QC Â Â based inSan Diego, CALIFORNIA (USA)
The World's First and Only CRISPR Analytics Platform. The Defining Technology of the 21st Century. The advent of CRISPR-Cas systems has enabled a new wave of advances in cell and gene therapies, plant and animal biology, and academic research. However, there are many roadblocks in the way of consistent editing outcomes. CRISPR QC allows you to realize the full potential of CRIPSR, with powerful ...
by:SeismiCat | ImageCat, Inc.  based inLong Beach, CALIFORNIA (USA)
SeismiCat provides an on-line seismic risk assessment tool for engineers serving building property owners, lenders, insurers and municipal analysts, consistent with ASTM E2026. The SeismiCat single-site tool uses USGS ground motions (2014 and 2008) computed directly for the relevant Site Class. User can inspect the hazards for the site location, including fault maps, Site Class, liquefaction ...