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Acute Toxicity Testing Articles & Analysis

69 articles found

The Predictive Potential of a Battery of Ecotoxicological Tests for Human Acute Toxicity, as Evaluated with the First 50 MEIC Chemicals

The Predictive Potential of a Battery of Ecotoxicological Tests for Human Acute Toxicity, as Evaluated with the First 50 MEIC Chemicals

Abstract : The acute toxicities of the first 50 chemicals (dextropropoxyphene hydrochloride excluded) of the multicentre evaluation of in vitrocytotoxicity (MEIC) programme were determined on four aquatic invertebrates and a bacterial strain (Photobacterium phosphoreumfor the MicrotoxTM test) commonly used in ecotoxicology ...

ByMicroBioTests Inc.


Toxicity and Microcystin Content of Extracts from a Planktothrix Bloom and Two Laboratory Strains

Toxicity and Microcystin Content of Extracts from a Planktothrix Bloom and Two Laboratory Strains

Additionally, different pre-treatments were used to break the cells before extraction. Acute toxicity was determined with the fairy shrimpThamnocephalus platyurus, subchronic effects were detected in embryos and larvae of the zebrafishDanio rerio. ...

ByMicroBioTests Inc.


Toxicity Studies of Treated Residual Wastes in Austria using Different Types of Conventional Assays and Cost-Effective Microbiotests

Toxicity Studies of Treated Residual Wastes in Austria using Different Types of Conventional Assays and Cost-Effective Microbiotests

Acute and chronic bioassays were carried out with a battery of test organisms. The acute toxicity was assessed using Daphnia magna (crustacea) and Vibrio fischeri (luminescent bacteria). The chronic toxicity was tested with Selenastrum capricornutum (green algae) and Lepidium sativum (a higher ...

ByMicroBioTests Inc.


Acute Toxicity Bioassays using Rotifers. - II. A Freshwater Test with Brachionus rubens

Acute Toxicity Bioassays using Rotifers. - II. A Freshwater Test with Brachionus rubens

Abstract : A 24 h acute toxicity test for freshwater is described using the rotifer Brachionus rubens hatched from cysts. ...

ByMicroBioTests Inc.


Cyst-Based Toxicity Tests. - III. Development and Standardization of an Acute Toxicity Test with the Freshwater Anostracan Crustacean Streptocephalus proboscideus

Cyst-Based Toxicity Tests. - III. Development and Standardization of an Acute Toxicity Test with the Freshwater Anostracan Crustacean Streptocephalus proboscideus

Abstract :A new method is presented for determination of the acute toxicity of chemicals and effluents to larvae of the freshwater anostracanStreptocephalus proboscideus(Frauenfeld), using resting eggs (cysts) as the source of test organisms. The larvae are obtained by controlled hatching of standard reference eggs. For the ...

ByMicroBioTests Inc.


Toxicity Monitoring of the Scheldt and Meuse Rivers in Wallonia (Belgium) by Conventional Tests and Microbiotests

Toxicity Monitoring of the Scheldt and Meuse Rivers in Wallonia (Belgium) by Conventional Tests and Microbiotests

Abstract : The Microtox acute toxicity test using the luminescent bacterium Vibrio fischeri, was chosen as a complementary descriptive parameter of toxic pollution in the framework of monitoring surface water quality in Wallonia, Belgium. ...

ByMicroBioTests Inc.


Acute Toxicity Tests with Streptocephalus Proboscideus (Crustacea / Branchipoda / Anostraca) : Influence of Selected Environmental Conditions

Acute Toxicity Tests with Streptocephalus Proboscideus (Crustacea / Branchipoda / Anostraca) : Influence of Selected Environmental Conditions

Abstract : The influence of selected environmental conditions on the acute toxicity of 3 selected chemicals (K2Cr2O7, CuSO4and Na pentachlorophenate) to instar II-III larvae ofStreptocephalus proboscideuswas evaluated. ...

ByMicroBioTests Inc.


Toxicity Assessment of Chemicals using Conventional Acute Daphnia magna Tests, Toxkits and Fluotox Microbiotests

Toxicity Assessment of Chemicals using Conventional Acute Daphnia magna Tests, Toxkits and Fluotox Microbiotests

The prerequisite for the use of Fluotox tests as (rapid) alternatives to acute toxicity tests is a good correlation of the results of the former with those of the latter. ...

ByMicroBioTests Inc.


Cyst-Based Toxicity Tests. - VI. The Potential of Ecotoxicological Tests for the Predicton of Acute Toxicity in Man as Evaluated on the First 10 Chemicals of the MEIC Programme

Cyst-Based Toxicity Tests. - VI. The Potential of Ecotoxicological Tests for the Predicton of Acute Toxicity in Man as Evaluated on the First 10 Chemicals of the MEIC Programme

Abstract : In the framework of the multicentre evaluation ofin vitrocytotoxicology (MEIC) programme, the first ten chemicals of the prescribed list were tested for acute toxicity in four standardised cyst-based aquatic invertebrate tests, consisting of two rotifer species (the estuarineBrachionus plicatilisand the ...

ByMicroBioTests Inc.


Acute Toxicity Bioassays using Rotifers. I. A Test for Brackish and Marine Environments with Brachionus plicatilis

Acute Toxicity Bioassays using Rotifers. I. A Test for Brackish and Marine Environments with Brachionus plicatilis

Abstract :A standardized 24-h acute toxicity test for the marine environment using the rotiferBrachionus plicatilisis described. ...

ByMicroBioTests Inc.


Canadian Application of Microbiotests to assess the Toxic Potential of Complex Liquid and Solid Media

Canadian Application of Microbiotests to assess the Toxic Potential of Complex Liquid and Solid Media

These include 1) adapting the Microtox® acute toxicity assay in a 96-well microplate format to markedly increase its sample throughput capabilities, 2) employing the SOS Chromotest™ to determine the genotoxic status of major industrial effluents discharging to the Saint-Lawrence River and their potential impact on downstream biota, 3) developing an ...

ByMicroBioTests Inc.


Comparison of Ukrainian Standard Methods and New Microbiotests for Water Toxicity Assessment

Comparison of Ukrainian Standard Methods and New Microbiotests for Water Toxicity Assessment

In order to determine the usefulness of some of these new microbiotests, comparative experiments have been carried out on the sensitivity of 2 Toxkit tests with the crustaceans Thamnocephalus platyurus and Daphnia magna, versus that of the crustacean Ceriodaphnia affinis and the protozoan ciliate Paramecium caudatum which are the test species indicated in the ...

ByMicroBioTests Inc.


The Use of a Battery of Microbiotests as a Tool for Integrated Pollution Control : Evaluation and Perspectives in Cyprus

The Use of a Battery of Microbiotests as a Tool for Integrated Pollution Control : Evaluation and Perspectives in Cyprus

In order to get a more holistic and synthetic evaluation of the ecotoxicological quality of the aquatic environment, the results from different toxicity tests are integrated and expressed in one single toxicological index. As a first step the results from the acute toxicity tests are integrated into a sub-index, ...

ByMicroBioTests Inc.


EPA Announces Start of Voluntary Pilot Program to Reduce Animal Testing

EPA Announces Start of Voluntary Pilot Program to Reduce Animal Testing

EPA states that the goal of the pilot program is to “evaluate the utility and acceptability of the GHS Mixtures Equation as an alternative to animal oral and inhalation toxicity studies for pesticide formulations.” For this pilot program, EPA is requesting submission of acute oral and acute inhalation toxicity study ...

ByBergeson & Campbell, P.C.


Toxicological and Environmental Safety Data - Case Study

Toxicological and Environmental Safety Data - Case Study

Toxicity Data Acute Oral Toxicity (Limit-Test) Approximate (A) LD50 > 5000 mg/kg body weight of up to 3 % (w/v) AGRAGEL as a gel in 0.9 % (w/v) saline applied with stomach tube to 5 male and 5 female rats each. ...

ByTerawet Green Technologies, Inc. (TGT)


A comparative approach using ecotoxicological methods from single‐species bioassays to model ecosystems

A comparative approach using ecotoxicological methods from single‐species bioassays to model ecosystems

As an important component of the ecologically relevant meiobenthic fauna, nematodes can be used for sediment assessments, with various assay tools ranging from single‐species toxicity tests to field studies. In this study, microcosms containing sediment to investigate direct and indirect effects of zinc on natural nematode assemblages, and acute ...

ByJohn Wiley & Sons, Ltd.


Post-treatment of sanitary landfill leachate by coagulation–flocculation using chitosan as primary coagulant

Post-treatment of sanitary landfill leachate by coagulation–flocculation using chitosan as primary coagulant

To evaluate the performance of the process using chitosan, we also carried out tests with aluminium sulphate (Al2 (SO4)3.14 H2O) as coagulant. In addition, acute toxicity tests were carried using the duckweed Lemna minor and the guppy fish Poecilia reticulata as test organisms. ...

ByIWA Publishing


The evaluation of three diets for rearing Hyalella azteca and the influence of diet on acute ammonia toxicity

The evaluation of three diets for rearing Hyalella azteca and the influence of diet on acute ammonia toxicity

The three diets were evaluated by comparing twenty weeks of culturing data, along with the organism's response to standard 96‐hour toxicity testing with ammonium chloride over a range of pH and temperature. ...

ByJohn Wiley & Sons, Ltd.


Comparative study on toxicity evaluation of anaerobically treated parboiled rice manufacturing wastewater through fish bioassay

Comparative study on toxicity evaluation of anaerobically treated parboiled rice manufacturing wastewater through fish bioassay

Short term aquatic bioassay has been developed into a useful tool in water quality management. These tests give information on comparative toxicity of several compounds. The objective of this study was to evaluate the acute toxicity of raw and anaerobically treated effluents of the parboiled rice manufacturing industry. The ...

ByIWA Publishing


Synergistic effect of piperonyl butoxide (PBO) on acute toxicity of pyrethrins to Hyalella azteca

Synergistic effect of piperonyl butoxide (PBO) on acute toxicity of pyrethrins to Hyalella azteca

A series of acute toxicity tests with the amphipod Hyalella azteca was performed to quantify the synergistic effect of piperonyl butoxide (PBO) on pyrethrins toxicity. PBO concentrations less than 4 µg/L caused no toxicity enhancement, while toxicity increased with PBO concentrations between ...

ByJohn Wiley & Sons, Ltd.

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