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Cardiac Output Articles & Analysis

7 articles found

The challenge of cardiovascular toxicity evaluation

The challenge of cardiovascular toxicity evaluation

The evaluation of cardiovascular toxicity is a significant challenge in drug development. Preclinical evaluation of cardiovascular safety involves a multifaceted approach, encompassing a plethora of in vitro and in vivo endpoints. These assessments continuously evolve, aiming to mitigate the incidence of cardiovascular toxicity that may emerge during clinical trials. To shed light on the ...

Byemka Technologies S.A.S


Pioneering Metabolism Studies through VOC Analysis: A Glimpse into Hiden Analytical’s Novel Approach

Pioneering Metabolism Studies through VOC Analysis: A Glimpse into Hiden Analytical’s Novel Approach

As a leader in patient-focused research, Hiden Analytical continuously pioneers innovative methods to understand human metabolism better. One significant aspect of our work is centred around the analysis of Volatile Organic Compounds (VOCs) present in human exhaled breath. These VOCs are key indicators of cellular metabolic activity, and our state-of-the-art mass spectrometry technology is ...

ByHiden Analytical Ltd.


Conceptual Considerations for Device-Based Therapy in Acute Decompensated Heart Failure

Conceptual Considerations for Device-Based Therapy in Acute Decompensated Heart Failure

The pathophysiology of fluid retention and mechanisms of diuretic resistance in acute decompensated heart failure (ADHF).A, Decreased cardiac output and blood pressure lead to activation of the renin-angiotensin-aldosterone axis, nonosmotic vasopressin release, and upregulation of the sympathetic nervous system. ...

BySecond Heart Assist, Inc.


The Use of High-Frequency Jet Ventilation in the Management of a Pre-term Infant with Pulmonary Stenosis and Respiratory Distress Syndrome. – A Case Report

The Use of High-Frequency Jet Ventilation in the Management of a Pre-term Infant with Pulmonary Stenosis and Respiratory Distress Syndrome. – A Case Report

The following day he was brought to the cardiac catheterization lab where he underwent a balloon dilation of the pulmonary valve. ...

ByBunnell Incorporated


Importance of hemodynamic monitoring during esophagectomy - Case Study

Importance of hemodynamic monitoring during esophagectomy - Case Study

Because of this risk, perioperative management of circulatory conditions such as hypovolemic hypotension is especially important to avoid postoperative heart complications, anastomotic leak, and conduit necrosis. The addition of continuous cardiac output monitoring provides advanced hemodynamic data that helps the anesthesia and surgical teams manage the patient ...

ByRetia Medical, LLC


Oxygen therapy for neurology

Oxygen therapy for neurology

Oxygen to increase the energy supplied to the brain The brain is known to utilize almost all oxygen and energy delivered, it receives about 20% of body oxygen, 15% of cardiac output and 25% of total body glucose to sustain about 5-10% of active neurons. ...

ByOXYHELP INDUSTRY


Cardiac toxicity by sublethal 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin correlates with its anti‐proliferation effect upon cardiomyocytes in zebrafish embryos

Cardiac toxicity by sublethal 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin correlates with its anti‐proliferation effect upon cardiomyocytes in zebrafish embryos

The cardiac toxicity of zebrafish embryos in response to the lethal dose of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) has been well characterized. ...

ByJohn Wiley & Sons, Ltd.

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