Refine by
Cholesterol Articles & Analysis
114 articles found
Research indicates chitosan can support weight management by binding dietary fats, help lower cholesterol, promote wound healing due to its antibacterial properties, and improve gut health as a prebiotic fiber. ...
ByMatexcel
When you hear the word "sterol," your mind probably jumps to one famous, and often misunderstood, molecule: cholesterol. We’re constantly bombarded with messages about "good" and "bad" cholesterol, and its impact on our cardiovascular health. But what if I told you that cholesterol is just one member of a vast and vital family of molecules ...
At its core, Lipid Metabolism encompasses the intricate biochemical processes involved in the synthesis, breakdown, and transport of fatty acids, cholesterol, and other lipid molecules. Cholesterol, often unfairly maligned, is actually the cornerstone of steroid hormone production. Through a series of sophisticated enzymatic reactions, primarily occurring in the ...
This diverse category includes statins for cholesterol management, antihypertensives like ACE inhibitors and beta-blockers, anticoagulants, and antidiabetic agents. ...
Exosomal lipids, such as sphingomyelins, phosphatidylserines, and cholesterol, are critical in regulating exosome biogenesis, membrane fusion, and interaction with recipient cells. ...
Their ingredients are produced in bacteria or yeast through genetic engineering and are fortified with vitamins, cholesterol, specific amino acids and fatty acids. Protein-free medium Protein-free media do not contain any protein, only non-protein components. ...
For example, fluorescein, biotin, magnetic beads, gold nanoparticles, etc. can be modified on nucleic acid aptamers for signal amplification or signal transduction; polyethylene glycol (PEG), cholesterol, etc. can be modified on nucleic acid aptamers to increase their solubility or circulation life; drugs, drug-loaded nanoparticles, etc. can be modified on nucleic acid aptamers ...
It contains monounsaturated fats, which are beneficial for heart health and can help lower bad cholesterol levels. Olive OilOlive oil is a staple in Mediterranean cuisine and is known for its high content of monounsaturated fats. ...
ByMatexcel
Investigators have explored various types of lipids, including cholesterol, phospholipids, and triglycerides, each offering unique properties that can influence the nanoparticles' behavior in vivo. ...
First, Cas9-sgPLK-1 plasmid/chondroitin sulfate (CS)/fish protein was used as the core (to make the whole highly concentrated, small and stable), and then cationic lipids (DOTAP/DOPE/cholesterol) were encapsulated (to improve the mechanical strength of the lipid layer) as the shell, and finally DSPE-PEG was used to further modify the whole (to increase stability, solubility and ...
Lipids are absorbed in two ways: triglycerides composed of medium- and short-chain fatty acids are absorbed after emulsification and enter the blood through the portal vein; triglycerides composed of long-chain fatty acids combine with apolipoproteins and cholesterol to form celiac particles and finally enter the blood through the lymph. ...
Furthermore, bile acids play a crucial role in the excretion of cholesterol and other waste products from the body, contributing to the maintenance of overall cholesterol homeostasis. In addition to their role in fat and cholesterol metabolism, bile acids possess antimicrobial properties, which can help to maintain a balanced gut microbiome and ...
In addition, supplementation of conventionally reared mice with specific bacterial strains resulted in increased body weight, elevated LDL and cholesterol levels, and altered expression of some genes involved in lipid transport. ...
Discovery of drug targets and lead compounds Many effective agents currently in use, such as cyclooxygenase inhibitors like rofecoxib and cholesterol-lowering drugs like simvastatin, target lipid metabolizing enzymes and thus regulate lipid metabolic networks. ...
Eat fruits and veggies, exercise regularly, do not smoke, and control high blood pressure, diabetes, and cholesterol. These are some age-old suggested habits that lead to a healthy lifestyle. ...
And the research team hypothesized that the high ratio of fusion DOPE may facilitate the fusion of LNP into cells through the inverted hexagonal H(II) phase to destroy the endosomal membrane, thereby enhancing protein translation and promoting the endosomal release of encapsulated mRNA. AA3-DLin/DOPE/ cholesterol /DMG-PEG molar ratio of 40:40:25:0.5 was finally determined to be ...
Polysaccharide-peptide complexes isolated from mulberry leaves can lower blood sugar in diabetic mice induced by streptozotocin and also reduce plasma triglycerides and cholesterol. The hypoglycemic mechanism of mulberry leaf peptides may stimulate insulin secretion, relieve the degradation and inactivation of insulin in peripheral tissues, thereby increasing insulin blood ...
Bile acids are specialized molecules synthesized from cholesterol within the liver. These amphipathic compounds possess a hydrophilic region (carboxylic acid moiety) and a hydrophobic region (steroid backbone). ...
Bile acids are synthesized in the liver from cholesterol as a raw material. As a natural "emulsifier", they can promote the dissolution, digestion and absorption of fats, fat-soluble vitamins, etc. ...
N- & C-terminal modification Terminal modifications include polyethylene glycol (PEG) modifications and cholesterol modifications, which are usually introduced into the 5' or 3' end of the sense sequence. PEG modification can increase particle size, shield negative charge, and reduce cytotoxicity, thus avoiding nuclease degradation and renal clearance of siRNA in vivo as well ...