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Chromatography Product Articles & Analysis
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The STEREO (Effective point-of-use Sterilization of medical equipment using Ethylene Oxide) project was an 18-month research initiative funded by GCRF, aimed at developing an innovative on-demand production system for ethylene oxide (EO) from ethanol. The project brought together researchers from the University of Cambridge (UoC), University of Johannesburg (UJ), and Botswana Institute for ...
Antibody drugs, as a type of therapeutic biological preparation, require not only precise bioengineering techniques for their production but also rely on a variety of raw materials and ancillary materials to support the production and stability of the drugs. ...
Host protein residues are a critical quality control parameter in biopharmaceutical production. Liquid chromatography-mass spectrometry (LC-MS) is a highly effective, highly sensitive, and highly accurate analytical technique, and it is an effective way to study host protein residues.Method Description1. ...
It is particularly useful for determining the drug-to-antibody ratio (DAR), identifying conjugation sites, and detecting potential degradation products. Techniques such as liquid chromatography-mass spectrometry (LC-MS) and matrix-assisted laser desorption/ionization (MALDI-MS) are commonly employed. High-Performance Liquid Chromatography ...
The use of thin-layer chromatography detection technology can quickly detect the biguanide ingredients in medical products and other substances, thus ensuring the quality and safety of medical products. Liquid Chromatography Liquid chromatography is a relatively common chromatographic detection technique. ...
Although the origins of world Laboratory Day are still unclear, it gives us a chance to reflect on the great achievements and breakthroughs in scientific research.At Techcomp, we are delighted to celebrate World Laboratory Day and to play our part with a suite of world-class laboratory products across Molecular Spectroscopy, Chromatography, Mass Spectroscopy, Gas ...
This requires the development of multi-step chromatography procedures with their respective product losses. Antibodies have set the gold-standard when it comes to a high-performing DSP platform thanks to Protein A affinity chromatography. ...
Processing/treatment control after production is beneficial to reduce unconjugated naked antibody and low/high DAR products, and control DAR within the target range. Therefore, drug loading and drug distribution are CQAs that should be controlled in ADC production. Spectroscopy, radiation, chromatography, mass spectrometry, etc. ...
This accounts for all segments of the market, including application of the product in pharmaceuticals, medicinal and therapeutic products, skin care products, and fiber/textiles. This growth, and the confidence in hemp products, will require applicable testing to ensure product quality and safety. ...
“Due to its versatility, the PrepChrom C-700 is a valuable instrument in our natural product isolation based research group, where preparative techniques such as column chromatography, flash chromatography and preparative HPLC are used on a daily ...
ByBUCHI
Abstract / Summary Waters is a leader in developing food and water quality testing systems that incorporate analytical standards and reagents, sample preparation products, chromatographic columns, instrumentation, and data management software. Our comprehensive solutions offer food and beverage laboratories the tools needed to check compliance with food and environmental regulations, decrease ...
Abstract / Summary Waters is a leader in developing food and water quality testing systems that incorporate analytical standards and reagents, sample preparation products, chromatographic columns, instrumentation, and data management software. Our comprehensive solutions offer food and beverage laboratories the tools needed to check compliance with food and environmental regulations, decrease ...
Further, the ultrasonic-combined Fenton process significantly enhanced the degradation rate to 95% of RB5 by the catalyst rGO/MnO2 NWs due to synergistic effects. The decomposition products identified using gas chromatography-mass spectrometry revealed a higher production rate of fragments in the ultrasonic-combined Fenton process. ...
Melamine is used as a profitable adulterant in milk based products to increase the protein content and thus increase the commercial value of the adulterated substance. In recent years Melamine and Cyanuric Acid has been found in infant formula and other milk based products. The presence of Melamine and Cyanuric Acid is highly regulated around the world. In this ...
As regulators focus in on the critical quality attributes (CQAs) of biotherapeutics, what can biopharmaceutical labs in late development or QC do to increase confidence in their bioseparations assays – other than to run additional orthogonal assays? Many labs are finding the answer in mass detection, specifically with the ACQUITY QDa Detector from Waters. Here are three ways that mass ...
GPSG Brazil adopted a laboratory information management system (LIMS) as part of its continuous focus on product quality. The company selected Thermo Scientific LIMS to improve efficiencies and product integrity and Thermo Fisher Scientific*s Atlas chromatography data system (CDS) to improve productivity in the laboratory. ...
A combination of non‐labelled and radio‐labelled 14C‐SFA was added to soil microcosms, with sampling and analysis protocols for soil, soil extracts and evolved CO2 established using liquid scintillation counting and liquid chromatography – mass spectrometry. Degradation products of SFA and their rates of formation were similar in the three soil types. The major ...
And finally, it allows for a single location to walk around and see over 17,000 companies and exhibitors with their products and technologies. Teledyne Technologies Incorporated will have 4 companies in attendance at Pittcon this year. ...
The impact of hydrogen peroxide to 1-naphthol ratio and activity of horseradish peroxidase was also studied. Size exclusion chromatography was used to estimate the molecular weight distribution of oligomeric products, and liquid chromatography/mass spectrometry was used to estimate product structure. ...
Capillary zone electrophoresis (CZE) with diode array detection was successfully used for the analysis of 2-methyl-4-chlorophenoxyacetic acid (MCPA) herbicide in an aqueous commercial plant protection product. The performance of the method was studied in terms of accuracy, precision, linearity, Limit of Detection (LOD) and Limit of Quantification (LOQ). ...
