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Chromatography Sample Preparation Articles & Analysis

7 articles found

Metabolomics Technologies in Medical Research

Metabolomics Technologies in Medical Research

HRMAS-NMR spectroscopy can be used for metabolic profiling of intact tissues without any sample pre-treatment and has been used to study metabolomic analysis of small intact tissue samples including brain, kidney, liver, etc. NMR spectroscopy does not require chromatographic processing. Sample preparation is simple and can be ...

ByCreative Proteomics


Protein Quantification Techniques and Their Application in Clinical Research

Protein Quantification Techniques and Their Application in Clinical Research

Introduction of HPLC-MS/MS-based Proteomics Technology The development of high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) based proteomics technology mainly depends on the liquid chromatography-mass spectrometry equipment, sample separation and preparation technology, identification, as well as ...

ByCreative Proteomics


Best practice for separation columns in ion chromatography (IC) - Part 2

Best practice for separation columns in ion chromatography (IC) - Part 2

The second part of this blog series about best practice for IC separation columns focuses on application related topics that have an impact on the column suitability and stability. First, there is the proper choice of the column that best suits the intended application. Then we turn to the operating parameters which can be modified in order to optimize the separation between analytes, and what ...

ByMetrohm AG


Some notes about Fats and Oils in Food and about FAME and FAMEWAX

Some notes about Fats and Oils in Food and about FAME and FAMEWAX

For this work, Annika Ostermann compared different derivatization and extraction procedures suitable for the determination of the fatty acid composition in plasma and tissues as fatty acid methyl esters using gas chromatography. Sample preparation and derivatization methods for the analysis of small amounts of tissue and low plasma volumes is ...

ByRestek Corporation


In Beverly, the Shoe Fits for Bioanalysis!

In Beverly, the Shoe Fits for Bioanalysis!

This past May, many of the nation’s leading bioanalysts gathered in New England to share ideas and explore the latest advances in mass spectrometry, liquid chromatography, and sample preparation for large molecule quantification. ...

ByWaters Corporation


Determining saccharidic tracers in atmospheric aerosols

Determining saccharidic tracers in atmospheric aerosols

They are best determined by ion chromatography coupled to pulsed amperometric detection. Sample preparation merely involves a simple waterextraction. ...

ByMetrohm AG


An overview of post-column derivatization methods from a pharmaceutical applications perspective

An overview of post-column derivatization methods from a pharmaceutical applications perspective

High performance liquid chromatography (HPLC) is the technique of choice for separating analytes pursuant to their detection, identification, quantification and/or purification. ...

ByPickering Laboratories, Inc.

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