Dna Microarray Articles & Analysis
9 articles found
While the fragmented DNA samples flow through the microarray, the complementary pairing effect will force exome binding at the microarray, while the other parts of the genome remain dissociative, which results in the separation of exome from other parts of the genome. ...
Recent advances in expression genomics have enabled the use of DNA microarray to profile gene expression of various cancers. These expression profiles may be suitable for molecular classification and prediction of disease outcome and treatment response. ...
Recent advances in expression genomics enable global transcript analysis that leads to molecular classification of cancers and prediction of outcome and treatment response. We did a cDNA microarray examination of the expression profiles of eight primary ovarian cancers stratified into two groups based on their chemotherapeutic response. We applied a ...
However, unlike associated diseases caused by genetic mutations, many epigenetic alterations are reversible, which offers optimistic prospects for disease treatment. What is A Gene Microarray? Microarray is also commonly known as gene chip, also known as DNA microarray. ...
In addition, SNPs can be used for genotyping, i.e., determining the proportion of each allelic variant combination at each nucleotide position. The basic principle of SNP microarrays is similar to that of DNA microarrays, consisting of a high density of oligonucleotide probes immobilized on a solid specific surface. Nucleic acids consisting of ...
Optical and electron microscopies, for example, are essential ways of observation when used in conjunction with various staining procedures. High-throughput DNA sequencing methods, for example, have swiftly produced large amounts of genetic information at minimal cost, making millions of microbial genomes available. ...
The technology was primarily developed for investigating interaction of fluids on a micrometer scale; however, biochemistry research largely benefited from microchips, enabling breakthroughs in single cell, DNA, protein and enzymatic analysis. Microfluidic platforms are suitable for optical detection technologies, magnetic manipulation, surface acoustic wave technology, and chip ...
A DNA microarray platform based on 2,200 genes from publicly available sequences was designed for Streptococcus thermophilus. We determined how single-nucleotide polymorphisms in the 65- to 75-mer oligonucleotide probe sequences affect the hybridization signals. The microarrays were then used for comparative genome hybridization (CGH) of 47 dairy ...
Under conditions of oxygen deprivation, the sigB gene is upregulated and cells exhibit high productivity of organic acids as a result of an elevated glucose consumption rate. Using DNA microarray and quantitative reverse transcription-PCR (RT-PCR) analyses, we found that sigB disruption led to reduced transcript levels of genes involved in the metabolism of ...