Hormone Active Articles & Analysis
15 articles found
Plant growth regulators (PGR) are a class of small molecule compounds with plant hormone activity that can affect plant growth and development. Such compounds are often used to enhance plant resistance, promote plant cell division and growth, increase yield, and improve quality. ...
Introduction Abaloparatide (ABL) is a bone-forming analog of human parathyroid hormone-related peptide (PTHrP) that is indicated for the treatment of postmenopausal women with osteoporosis (PMO) at high risk of fracture.(1) In the pivotal phase 3 ACTIVE study in women with PMO, 18 months of ABL treatment increased areal bone mineral density (aBMD) at the ...
These assays are typically performed in immature rats and may be influenced by the strain selected in addition to numerous environmental conditions. The basis for hormone potency assays is typically a parallel line analysis in which the biological activity of the given hormone is estimated by comparing its effect on reproductive organs. ...
AbstractArxula adeninivorans-based yeast cell assays for the detection of steroid hormones demonstrated their efficiency for the determination of total hormone activity in a variety of samples using a microtiter plate format. In this study, a preliminary chromatographic separation using thin-layer chromatography plates is introduced in order to ...
Scientists tie the condition directly to exposure to hormones or endocrine-disrupting chemicals put in the water by industrial processes or through contaminants in wastewater discharges. ...
They describe fish and birds responding with altered behavior and reproductive systems to antidepressants, diabetes medication, and other psychoactive or hormonally active drugs at concentrations found in the environment. They report on opiods, amphetamines and other pharmaceuticals found in treated drinking water; antibiotics in groundwater capable of altering ...
ByEnsia
Hormonally active compounds may move with agricultural runoff from fields with applied manure and biosolids into surface waters where they pose a threat to human and environmental health. Riparian zone plants could remove hormonally active compounds from agricultural runoff. Therefore, sorption to roots, uptake, translocation, ...
Chemical analyses were conducted on surface water samples at each site in both the spring and fall for pesticides, hormones, active pharmaceutical ingredients (APIs). APIs were more often detected across sampling events in the fall; however, at the most downstream site the number of analytes detected and their concentrations were greater in the spring, which may ...
The trigger is the lack of or reduced effectiveness of the body's own insulin; a hormone which is produced in the pancreas. The main function of insulin is the regulation of the concentration of glucose in the blood. ...
Chemical analysis of 17β‐estradiol, estrone and 17α‐ethinylestradiol levels showed that they accounted for the majority of the observed in vitro estrogenic activity in the final effluents but only 18 to 70% of estrogenic activity in the influents. Removal efficiency for androgenic activity was 97.5 to 100%. Endocrine activity ...
The incorporation of brominated flame retardants into industrial and household appliances has increased their occurrence in the environment resulting in deleterious effects on wildlife. With the increasing restraints on available compounds there has been a shift to using BFRs that has seen the production of alternative BFRs such as 1,2‐dibromo‐4‐(1,2 dibromoethyl) cyclohexane (TBECH). TBECH ...
Reporter gene assays were used to detect receptor‐mediated (anti‐)estrogenic, (anti‐)androgenic, and (anti‐)thyroid hormone activities. The effect of PFOS on steroidogenesis was assessed both at hormone levels in the supernatant and at expression levels of hormone‐induced genes in the H295R cell. ...
Observed differences included lower plasma concentrations of thyroid hormones and/or elevated liver deiodinase activity. Histological evaluation of the thyroid tissue indicated that in the case of female goldfish, those perturbations stimulated the thyroid (as indicated by increased thyroid epithelial cell height) and partially depleted the thyroxine reserves, as ...
Wastewaters from various industries are a main source of the contaminants in aquatic environments. The authors evaluated the hormonal activities (estrogenic/anti‐estrogenic activities, androgenic/anti‐androgenic activities) and genotoxicity of various effluents from textile and dyeing plants, electronic and electroplate ...
In practice it was reported that chronic exposure to perchlorate may lead to damage in thyroid hormone activity. This study introduced a method of perchlorate reduction, using autotrophic bacteria which utilise hydrogen as an electron donor. ...