Immunoassay Development Articles & Analysis
5 articles found
Advancements in microfluidics, detection strategies, antibody engineering, and immunoassay readers are driving the development of novel "next-generation" rapid POC diagnostics, with sensitivity approaching that of current "gold standard" clinical analyzers. There is a growing demand for higher-content readings in immunoassay formats, thus the ...
Biotin-Avidin-System (BAS) is a new type of biological reaction amplification system developed in the late 1970s. The high-affinity strong binding between biotin and avidin and the multi-level amplification effect make BAS immunolabeling and related tracer analysis more sensitive. With the deepening of the research on the three-dimensional structure, binding characteristics and ...
It may be related to factors such as infection, endocrine dysfunction, and immune dysregulation. MMP-3 is involved in the development of SLE by degrading the vascular matrix components in SLE patients' blood vessel walls. ...
Steroid hormone assays entered clinical use as early as the 1950s, with the parallel development of biochemical immunoassays and mass spectrometry. Early methods included enzyme bioassays and chemical assays, which applied colorimetric and fluorometric detection for analysis, respectively. However, these methods were limited to the analysis of urine samples. ...
To investigate whether 11‐ketotestosterone (11‐KT) or its immunoreactive metabolites are formed and excreted in ruminant feces, an enzyme immunoassay (EIA) was developed and validated. The antibody was raised in rabbits against 11‐KT‐3‐CMO:BSA with biotinylated 11‐KT as a label. ...