In Vitro Cellular Articles & Analysis
6 articles found
These models can be broadly categorized into two main groups: cellular models and animal models. Cellular models primarily involve the use of hepatocyte cell lines or primary hepatocytes isolated from animal sources. Such models allow for controlled studies in vitro, facilitating the examination of cellular mechanisms, lipid ...
Furthermore, their ability to infect both immortalized and primary cells significantly broadens their scope of use in vitro and in vivo studies. Concept of Reporter Lentiviral Particles Reporter lentiviral particles carry the technology a step further by including a reporter gene in the viral vector. ...
” ISO Publishes Standard On Use And Application Of Acellular In Vitro Tests And Methodologies To Assess Nanomaterial Biodurability: In October 2017, the International Organization for Standardization (ISO) published standard ISO/TR 19057:2017, “Nanotechnologies -- Use and application of acellular in vitro tests and methodologies to assess ...
Changes in protein expression as a cellular response to chemical exposure have been well established. Current methods for monitoring cellular responses usually require the use of specific reagents and/or labor‐intensive procedure. In this study, the concept on using mass spectral pattern to distinguish different cellular responses is demonstrated. The concept is based on the ability to acquire ...
New high-throughput screening tools such as those housed at the NCGC, other in vitro (cellular) assays, and computational methods are enabling the assessment of an astonishing number of chemicals efficiently and quickly. ...
It is now known that low doses and dose rates of certain agents (e.g., radiation and genotoxic chemicals) can induce protective processes that together lead to a reduction in mutations and neoplastic transformation below the spontaneous frequency in mammalian in vitro and in vivo cellular communities. However, after high doses, some of the protection is lost, ...