Intraperitoneal Injection Articles & Analysis
6 articles found
Evaluating the stress related effects of various restraint methods in rodents Any restraining device used in an inhalation exposure set-up will be, by definition, restricting the subject’s ability to move. For nose-only inhalation set-ups, typical restraints are rigid, fully enclosed and include a metal or acrylic plunger forcing the subject forward and preventing the subject from ...
By combining CPP (8K, octa-yLysine) with NF-κB essential regulator binding domain (NBD), Dave et al. treated mice with inflammatory bowel disease by intraperitoneal injection. The results showed that the activation of NF-κB was inhibited in the treated mice, and inflammatory cytokines TNF-α, IL-6 and IL-1 showed a decreasing trend, and ...
A test was carried out by combining CPP (8K, Octylysine) with NF-κB essential regulator binding domain (NBD), and then treating mice with inflammatory bowel disease by intraperitoneal injection. The results showed that the intestinal inflammation was improved in the treated mice since the activation of NF-κB was inhibited and the inflammatory ...
Furthermore, these compounds exhibited a 5- to 10-fold LDLR upregulation at 1.6 μM in two recombinant cell-based assays as well as exhibited an increase in the fluorescently labeled DiI-LDL uptake in situ in the nanomolar range. In animal studies, intraperitoneal (IP) injection of these compounds administered alone resulted in more than 20% reduction in LDL-C ...
DNA damage in blood and liver cells was analysed by the comet assay and micronucleus test (MN). Mice were injected intraperitoneally with the following treatments: (a) physiological saline, (b) treated water, (c) treated water plus C. raciborskii extract (CYN producer strain, CYPO-011 K), (d) C. raciborskii extract (CYN producer strain, CYPO-011 K), (e) C. ...
Then the mice were decapitated at either 6 h or 72 h after whole-body IR, where intraperitoneal injections of EGb or saline were repeated once daily. Human peripheral lymphocytes were observed for the determination of the frequencies of apoptotic cells. ...