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Kidney Dysfunction Articles & Analysis

12 articles found

Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor

Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor

Ferrostatin-1 inhibits cell death in cellular models of Huntington's disease (HD), periventricular leukomalacia (PVL), and kidney dysfunction[2]. Ferrostatin-1 (1 μM; 6 h) inhibits the oxidative destruction of unsaturated fatty acids in HT-1080 cells, thus increases the number of healthy medium spiny neurons ...

ByMedChemExpress LLC (MCE)


Cytokine Involvement in Inflammatory Immune Disorders

Cytokine Involvement in Inflammatory Immune Disorders

Inflammatory effectors are key cytokines driving major clinical symptoms, like INF-γ inducing fever and hematopoiesis, TNF-α causing fever and depression, and IL-6 contributing to fever, acute kidney injury, and NK cell dysfunction. Inflammation initiation factors involve virus recognition by macrophage pattern receptors, triggering inflammasome ...

ByCreative Proteomics


What causes heart failure with preserved ejection fraction (HFpEF)?

What causes heart failure with preserved ejection fraction (HFpEF)?

Heart failure with preserved ejection fraction (HFpEF) is a multifactorial and multisystemic disorder that represents more than 50% of all heart failure cases.[1] Epidemiologic data from the Framingham Study, an international cohort study, shows a rapid increase in the prevalence of HFpEF over the past three decades, from 41% to 56% and, conversely, a decrease in the prevalence of HFrEF from 44% ...

ByUltromics Limited


Mass Spectrometry-Based Metabolomics

Mass Spectrometry-Based Metabolomics

Bile acids are also closely associated with the development of degenerative liver and kidney diseases, chronic inflammation, intestinal mucosal dysfunction, biliary stasis, and cancer. ...

ByCreative Proteomics


A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury

A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury

Abstract Purpose: We evaluated Galectin-3 (Gal-3) as a potential early biomarker of acute kidney disease (AKI), and the effect of Gal-3 inhibition by modified citrus pectin (P-MCP) on renal ischemia/reperfusion (I/R) induced AKI. ...

ByEliaz Therapeutics


How to support healthy blood sugar levels.

How to support healthy blood sugar levels.

Maintaining healthy blood sugar levels can help reduce the risk of developing diabetes, kidney dysfunction, and problems with your eyes, gums, and nerves. Day-to-day healthy blood sugar levels will help with balancing energy levels, maintaining focus, and stabilizing mood. ...

ByAmyris Biotechnologies, Inc.


3 Things That Google’s Healthcare Artificial Intelligence Desperately Needs

3 Things That Google’s Healthcare Artificial Intelligence Desperately Needs

Google DeepMind recently published a paper in Nature that shared how their predictive algorithm can detect Acute Kidney Injury (AKI) up to 48 hours in advance. Acute Kidney Injury is the biggest problem you have never heard of. ...

ByPotrero Medical


4 Benefits of Electrocoagulation for Heavy Metal Wastewater Treatment

4 Benefits of Electrocoagulation for Heavy Metal Wastewater Treatment

There is much debate in academia, as to what elements should be considered “heavy metals”. Some criteria depend on density, some on atomic number, and some on chemical behavior. In the water treatment industry, we tend to concern ourselves with the more common and more toxic variety. Such heavy metals may include mercury, cadmium, lead, chromium, and copper. Arsenic is also ...

ByGenesis Water Technologies, Inc.


Nitrate Pollution Affects Millions in U.S.

Nitrate Pollution Affects Millions in U.S.

At higher levels in drinking water, it is associated with health effects including bladder, thyroid, and kidney cancer; thyroid dysfunction; birth defects; low birth weight; and premature birth. ...

ByFluence Corporation


The Hidden Danger Of Air Quality in Indoor Firing Ranges

The Hidden Danger Of Air Quality in Indoor Firing Ranges

It has been proven to create symptoms such as abdominal pains, fatigue, high blood pressure, memory loss, kidney dysfunction and other severe forms of mental and physical impairment. ...

ByCamfil UK Ltd


Commission Finally Proposes Limits on Cadmium in Fertilisers

Commission Finally Proposes Limits on Cadmium in Fertilisers

The concern underlying the strategy was the need to reduce direct human exposures to the metal and limit its accumulation in soils where it is available for uptake by crops. Cadmium accumulates in human kidneys and can cause renal dysfunction in vulnerable groups, and the margin of safety between current exposures and concentrations at which health effects can ...

ByEnvironmental News and Data Services (ENDS)


Heavy Metals in Waste

Heavy Metals in Waste

Cadmium Cadmium accumulates especially in the kidneys leading to dysfunction of the kidney with increased secretion of e.g. proteins in urine (proteinuri) and other effects. ...

ByEuropean Commission, Environment DG

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