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Liquid Chromatography Articles & Analysis
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Alternatives and Modern Approaches Although the ninhydrin method is widely used, other techniques can provide greater accuracy or sensitivity: l High-Performance Liquid Chromatography (HPLC): Separates and quantifies free amino acids with excellent precision. ...
Polystyrene microplastics (PSMPs), small plastic fragments measuring less than 5 µm in diameter, are increasingly recognized as harmful air-borne pollutants. Studies demonstrate their ability to penetrate deep into the lungs, where they can induce oxidative stress, inflammation and airway remodeling. A recent study by Balkrishna et al. (2025) investigates these effects in a murine model and ...
How IC is helping us provide more accurate, reliable, and insightful environmental solutions. Ion chromatography (IC) is an analytical chemistry technique to analyze ions and polar molecules via liquid chromatography. This is a separation technique that uses a liquid mobile phase to separate components of a mixture, based on ...
Mass Spectrometry (LC-MS/MS): This enriched sample is then analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). This highly sensitive technique measures the mass of the protein fragments, allowing for their precise identification and even pinpointing the exact site of ubiquitination. ...
Common Application Cases of Nanocellulose Nanocellulose can also be used as various medical materials (drug sustained release, medical implants, biological tissue engineering, antibacterial agents, ), ion adsorption and exchange materials, biofunctional materials (immobilized enzyme carriers, DNA marker biosensors, bioimaging, endotoxin adsorbents), etc., and is expected to prepare cellulose ...
Among available techniques, gas chromatography-mass spectrometry (GC-MS) remains the gold standard due to its sensitivity, reproducibility, and specificity. ...
By comprehensively profiling these molecules using advanced analytical platforms – predominantly mass spectrometry (MS) coupled with liquid (LC-MS) or gas chromatography (GC-MS), and nuclear magnetic resonance (NMR) spectroscopy – we gain unprecedented insights. ...
Because steroid hormones are present in relatively low concentrations and often exist as a complex mixture of structurally similar compounds, their accurate identification and quantification require highly sensitive and specific analytical techniques. Advanced methods, such as liquid chromatography-tandem mass spectrometry (LC-MS/MS), are indispensable tools. ...
Techniques like protein precipitation, liquid-liquid extraction (LLE), and solid-phase extraction (SPE) are commonly used to isolate and enrich target compounds from biological or food matrices. 2. Chromatographic Techniques High-resolution separation methods such as High-Performance Liquid Chromatography (HPLC), ...
Combined with advanced mass spectrometry and chromatography techniques, these services primarily employ two complementary approaches: untargeted lipidomics and targeted lipidomics. ...
The pharmaceutical industry is under constant pressure to ensure product integrity, regulatory compliance, and efficiency in manufacturing. As production processes become more complex, the need for real-time, data-driven quality control has never been greater. Near-infrared (NIR) spectroscopy is essential for advanced monitoring of drug manufacturing, enabling rapid, non-destructive analysis ...
Pharmaceutical manufacturers face growing challenges in ensuring product quality, maintaining regulatory compliance, and safeguarding against counterfeit drugs. Near-infrared (NIR) spectroscopy is an important tool in this arena, offering rapid, non-destructive analysis for raw material identification, impurity detection, and counterfeit screening. By integrating NIR spectroscopy into quality ...
Purity and Concentration Analysis ServicePurity and concentration analysis is a fundamental service that assesses the quality of the RDC drug before it progresses to further testing. High-performance liquid chromatography(HPLC) and mass spectrometry (MS) are commonly employed techniques in this analysis. ...
Techniques for Plant Hormone Analysis Advanced analytical techniques are employed to measure and analyze plant hormones: Chromatographic Techniques: High-performance liquid chromatography (HPLC) and gas chromatography (GC) are widely used to separate and quantify hormones due to their specificity and sensitivity. ...
Here are some common methods: High-Performance Liquid Chromatography (HPLC): HPLC is one of the most widely used methods for vitamin analysis. ...
Analytical Chemistry: Methods like HPLC (High-Performance Liquid Chromatography) and mass spectrometry can be used to analyze secreted products, confirming the functional characteristics of the cells. ...
One of the most effective methods is mass spectrometry (MS), often combined with liquid chromatography (LC-MS). This technology enables the detailed identification and quantification of lipids and metabolites from small samples like exosomes, which are typically limited in number. ...
Creative Proteomics offers specialized glucosinolates analysis services using advanced technologies like LC-MS and GC-MS, enabling researchers to identify, quantify, and profile glucosinolates in various sample types. Key Analytical Techniques Liquid Chromatography-Mass Spectrometry (LC-MS): LC-MS is the gold standard for glucosinolate analysis. It provides ...
Common approaches include: High-Performance Liquid Chromatography (HPLC): This is a reliable and widely used method for separating and quantifying NAD and NADH in complex biological samples. ...
Additionally, amino acid determination can also be used to monitor the levels of amino acids in biological samples, which is important for studying the pathogenesis and treatment effects of various diseases.Common Methods of Amino Acid Determination1. High-Performance Liquid Chromatography (HPLC)(1) PrincipleHPLC can separate, identify, and quantify various ...