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Lung Functionality Articles & Analysis
70 articles found
The GOLD 2024/2025 reports emphasize that spirometry is required to establish the diagnosis of COPD, with a post-bronchodilator FEV1/FVC < 0.7 serving as the defining criterion for persistent airflow limitation in the appropriate clinical context.Health awareness campaigns have also highlighted the value of lung function testing. For instance, World COPD Day ...
Introduction Many industrial workshops invest in fume extraction systems but still struggle with poor air quality, visible smoke, and inconsistent system performance. These issues are typically not due to the absence of equipment, but rather improper system design, incorrect usage, or lack of maintenance. As a result, common welding fume extraction problems persist despite the presence of ...
Introduction Fabrication shops rely heavily on welding processes such as MIG, TIG, and arc welding to manufacture structural components, assemblies, and custom metal products. While these processes are essential to production, they generate significant amounts of welding fumes consisting of fine metal particles and gases. In enclosed or semi-enclosed fabrication environments, these contaminants ...
Long-term exposure to fine particulate matter and combustion-derived particles is associated with respiratory irritation, reduced lung function, and elevated occupational health risks for workers in roles such as welding and engine testing.From an operational perspective, deposition of soot on machinery, sensors, and equipment introduces calibration challenges, ...
In the world of preclinical lung cancer research, seeing a tumor is only half the battle. While traditional imaging like microCT can show us where a mass is located, it often fails to tell the full story: How is that tumor actually affecting the animal’s ability to breathe? A recent pilot study by Smith et al (2025) has broken new ground by combining two powerhouse ...
Polystyrene microplastics (PSMPs), small plastic fragments measuring less than 5 µm in diameter, are increasingly recognized as harmful air-borne pollutants. Studies demonstrate their ability to penetrate deep into the lungs, where they can induce oxidative stress, inflammation and airway remodeling. A recent study by Balkrishna et al. (2025) investigates these effects in a murine model and ...
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. Current therapies for IPF rely on oral administration of pirfenidone and nintedanib, two FDA-approved drugs that slow disease progression. While ...
A recent study by Marain et al. (2025) develops a murine model to investigate the combined effects of cold air, diesel exhaust particles (DEP) and exercise on lung physiology and airway inflammation. By integrating SCIREQ’s flexiVent and Double Chamber vivoFlow+ Plethysmography, the group captures both non-invasive breathing patterns and invasive, high-resolution ...
In the rapidly advancing realm of respiratory medicine, relying solely on spirometry is insufficient for achieving precise lung function diagnoses. Compared with spirometry, the Diffusion Capacity of the Lung for Carbon Monoxide (DLCO) test can obtain deeper insights into lung functions, leading to its widespread ...
Have you started snoring suddenly and have other health issues that have emerged recently? Although snoring is usually considered as a harmless annoyance, it is actually a symptom of deeper health issues, such as hypothyroidism. This is when the thyroid reduces the production of thyroid, a vital hormone and there is a deficiency in the body. Though the connection between hypothyroidism and ...
Research in the field of pulmonary biology often requires detailed analysis of lung tissues. One of the optimal methods for studying lung structures and functions in mice is the use of C57 mouse models, specifically through the preparation of frozen sections. ...
Air pollution, especially fine and ultrafine particles, poses significant health risks to older adults. Seniors are more vulnerable due to age-related declines in immunity and chronic health conditions, leading to higher rates of respiratory and cardiovascular disease, cognitive decline, and increased mortality. Reducing exposure - through policy changes, personal precautions, and community ...
Air pollution is a well-known health risk, but one of its most dangerous components is often invisible: ambient ozone. Unlike particulate matter or smoke, ozone isn’t something you can see or feel immediately. However, its impact on human health is profound. Ozone at ground level is a major component of smog and is formed when pollutants from vehicle emissions, industrial facilities, and ...
Smokers significantly increase the risk of developing Chronic Obstructive Pulmonary Disease (COPD) and lung cancer, as well as heart disease. The good news is quitting smoking brings immediate and long-term health benefits, reducing health risks and improving overall well-being. ...
Ozone serves as a protective layer in the upper atmosphere, absorbing harmful ultraviolet rays and helping sustain life on Earth. But at ground level, ozone transforms into a pollutant that can damage ecosystems, deteriorate infrastructure, and harm human health. This “ambient ozone” is a byproduct of chemical reactions between pollutants, such as nitrogen oxides (NO?) and volatile ...
Ambient ozone is a significant component of atmospheric chemistry, influencing air quality and human health. While ozone (O3) plays a crucial protective role in the upper atmosphere by shielding the Earth from harmful ultraviolet radiation, its presence at ground level—often referred to as ambient or tropospheric ozone—poses serious environmental and health risks. Understanding ...
Sleep apnea is a sleep disorder that is characterized with snoring and frequent interruptions in breathing, when asleep. That impacts quality sleep and puts the individual at risk of health issues. Though CPAP therapy is considered gold standard in treating sleep apnea, there are a multitude of vitamins and minerals that can help you get better sleep by addressing factors like muscle relaxation ...
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
Our aim is for anyone with asthma to have: · No daytime symptoms, · No night symptoms, · No activity limitations, · No need for using a rescue inhaler, · No side effects from treatment, · Normal lung function. The main part of treating asthma is treating the underlying ...
This enzyme is known for its ability to degrade elastin, a key protein that provides elasticity and resilience to tissues such as skin, lungs, and blood vessels. Understanding the functions and implications of elastase is crucial in biochemistry and medicine, as it has a significant impact on both health and disease. ...