Refine by
Lung Tissue Articles & Analysis
55 articles found
Key findings Reduced lung injury: decreased cellular apoptosis and tissue damage. Improved mitochondrial health: lower oxidative stress within lung cells. ...
In the world of preclinical lung cancer research, seeing a tumor is only half the battle. While traditional imaging like microCT can show us where a mass is located, it often fails to tell the full story: How is that tumor actually affecting the animal’s ability to breathe? A recent pilot study by Smith et al (2025) has broken new ground by combining two powerhouse technologies - ...
Why Welding Fumes Are a Serious Health Concern Welding creates fumes that contain fine metal particles and gases. These fumes enter the lungs when workers breathe. Over time, repeated exposure causes serious health problems. Many of these risks do not appear immediately. They build slowly and affect workers years ...
Polystyrene microplastics (PSMPs), small plastic fragments measuring less than 5 µm in diameter, are increasingly recognized as harmful air-borne pollutants. Studies demonstrate their ability to penetrate deep into the lungs, where they can induce oxidative stress, inflammation and airway remodeling. A recent study by Balkrishna et al. (2025) investigates these effects in a murine model and ...
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. ...
The effectiveness of ELANE as an antimicrobial enzyme is supported by in vivo studies showing increased susceptibility to bacterial infections in ELANE-deficient models. Dysregulation and Tissue Damage: The Inflammatory Trade-off While ELANE is crucial for defense, its unregulated activity is a major contributor to inflammatory tissue injury. The enzyme can ...
Research in the field of pulmonary biology often requires detailed analysis of lung tissues. One of the optimal methods for studying lung structures and functions in mice is the use of C57 mouse models, specifically through the preparation of frozen sections. ...
Air pollution, especially fine and ultrafine particles, poses significant health risks to older adults. Seniors are more vulnerable due to age-related declines in immunity and chronic health conditions, leading to higher rates of respiratory and cardiovascular disease, cognitive decline, and increased mortality. Reducing exposure - through policy changes, personal precautions, and community ...
Sleep apnea is a sleep disorder that is characterized with snoring and frequent interruptions in breathing, when asleep. That impacts quality sleep and puts the individual at risk of health issues. Though CPAP therapy is considered gold standard in treating sleep apnea, there are a multitude of vitamins and minerals that can help you get better sleep by addressing factors like muscle relaxation ...
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
This enzyme is known for its ability to degrade elastin, a key protein that provides elasticity and resilience to tissues such as skin, lungs, and blood vessels. Understanding the functions and implications of elastase is crucial in biochemistry and medicine, as it has a significant impact on both health and disease. ...
As it enters the bloodstream, it can prevent your body from adequately absorbing oxygen, resulting in tissue damage and, ultimately, death. Concentration: 10 mg/m3 – Maximum daily 8 hour mean Lead (Pb): Lead is especially harmful to children, whose growth can be prevented even at low levels. ...
They are present in most connective tissues. MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, and MT1-MMP and MT3-MMP are expressed in various vascular tissues and cells. ...
Additionally, fine particulate matter (PM2.5) emitted during incineration poses a significant risk to human health, penetrating deep into the lungs and bloodstream. Health Risks 1. Respiratory Issues Exposure to the toxic emissions from plastic incineration can result in respiratory ailments such as asthma, bronchitis, and chronic obstructive pulmonary disease (COPD). Fine ...
To understand the physiological systems that may drive these behavioral changes, Ross's team investigated how widespread microplastic exposure is in the body, dissecting several major tissues, including the brain, liver, kidneys, gastrointestinal tract, heart, spleen and lungs. ...
ByMatexcel
Arsenic trioxide (ATO) is an inorganic arsenical that poses significant environmental and public health risks due to its toxic nature. While it is widely used in various industrial and medicinal applications, the potential harm caused by intentional or accidental exposure cannot be overlooked. Despite its prevalence, the pulmonary pathology resulting from acute high-dose exposure to ATO has not ...
Hemoglobin: The protein responsible for transporting oxygen from the lungs to the tissues is a marvel of nature. Intact mass analysis of hemoglobin helps researchers understand its molecular weight, the presence of post-translational modifications, and even the detection of variant forms. ...
They already have been found in our own lung tissue, GI tracts, bloodstreams, and breast milk. They’re microplastics, the small shards, particles, and fibers that result from the breakdown of plastic items, and they’re virtually everywhere. ...
We compared the differential gene expression in non-small cell lung cancer (NSCLC) between two platforms in order to find the most relevant genomic signatures of tumor recurrence. Materials and Methods We analyzed gene expression in frozen lung cancer tissue from 59 selected patients who had undergone surgical resection of NSCLC. ...
This DDS also prevents topical stimulation of lung tissue and reduces drug toxicity. Using surface-bound ligands or antibodies, the most significant advantage of liposome formulations for pulmonary administration application is the targeting of specific cell populations.Enhance antibiotic efficacy and safetyMany factors hinder the effective therapeutic effects of ...