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Microfluidic Device Articles & Analysis

24 articles found

Microfluidics Revolution: Polystyrene Particles Powering Miniaturized and Automated Immunoassays

Microfluidics Revolution: Polystyrene Particles Powering Miniaturized and Automated Immunoassays

The adoption of disposable microfluidic-based devices can meet diagnostic needs with minimal additional instrumentation. ...

ByCD Bioparticles


Application Spotlight: Fluoropolymers use in home healthcare

Application Spotlight: Fluoropolymers use in home healthcare

The home healthcare market is experiencing rapid growth as patients seek more convenient, comfortable care outside of hospitals. Whether managing chronic conditions, receiving post-operative care, or utilizing wearable medical devices, patients and providers alike demand medical components that are safe, reliable, and effective in non-clinical settings. Fluoropolymer tubing—PTFE, PFA, and ...

ByFluorostore


Exosomal RNA Sequencing: A Comprehensive Guide

Exosomal RNA Sequencing: A Comprehensive Guide

Alternatively, technologies such as nanoparticle-tracking analysis and microfluidics-based devices offer faster and more streamlined approaches. l RNA Extraction: The RNA is then extracted from the isolated exosomes. ...

ByCreative Biostructure


Etchants: Advancements in Semiconductor Technologies, and Energy Sector

Etchants: Advancements in Semiconductor Technologies, and Energy Sector

Moreover, biomedical etchants are employed in the production of microfluidic devices. These devices are used in biotechnology and medical research to manipulate and analyze tiny amounts of fluids, such as blood samples or biological reagents. ...

ByAlfa Chemistry


VIEW Tech Bulletin - Critical Dimension Measurement

VIEW Tech Bulletin - Critical Dimension Measurement

Critical Dimension Measurement is crucial in industries where precision matters most. Imagine making the tiniest parts for your smartphone or the chips that power your computer. Getting those sizes right is critical. Let’s explore why measuring these dimensions accurately is so important and how it’s ...

ByVIEW Micro Metrology


Bio-Ink: Printing the Future of Medicine and Beyond

Bio-Ink: Printing the Future of Medicine and Beyond

Biofabrication: Bio-ink can be used to create complex biological structures for research and development, such as microfluidic devices for drug delivery. Challenges and Future Directions Despite its immense promise, bio-ink technology is still in its early stages of development. ...

ByMatexcel


The Methods of Whole Genome Sequencing

The Methods of Whole Genome Sequencing

Subsequently, these library fragments can be amplified in situ by hybridization and extension from complementary adapters which are covalently attached to the surface of a glass microfluidic cell or a small bead (depending on the sequencing platform). All NGS instruments utilize a microfluidic device to contain the amplified fragments of the ...

ByCD Genomics


Spatial profiling of chromatin accessibility in mouse and human tissues

Spatial profiling of chromatin accessibility in mouse and human tissues

Fabrication and assembly of the microfluidic device The moulds for microfluidic devices were fabricated in the cleanroom using standard photolithography. ...

ByAtlasXomics Inc.


Tackling the Global Vaccine Distribution Challenge

Tackling the Global Vaccine Distribution Challenge

A breakthrough in nanotechnology accelerates vaccine production While COVID-19 hotspots have continued to emerge driven by the Delta variants, the data still shows that vaccinations are effective at preventing hospitalizations and deaths. While over 4 billion vaccine doses have been administered worldwide, only 27% of the world’s population and only 1.1% of people in low-income countries ...

ByChemical Abstracts Service (CAS)


Scottish startup approach Integrated Graphene to develop a Bovine Tuberculosis sample preparation device - Case study

Scottish startup approach Integrated Graphene to develop a Bovine Tuberculosis sample preparation device - Case study

A Scottish startup organisation devised an application-based solution to develop an assay with increased sensitivity and specificity to monitor TB infections in the field but did not have the technical experience to develop the microfluidic components to prepare and deliver the sample. The startup approached us to take advantage of our microfluidics expertise and ...

ByiGii (formely known as Integrated Graphene Ltd)


Accurately Recapitulating Environmental Niches in  Vitro Models of the Intestine

Accurately Recapitulating Environmental Niches in Vitro Models of the Intestine

This approach also makes our platforms simple to use; no pumps or complex systems are required, as with microfluidic devices. RepliGut® Planar Our workhorse platform is a planar model (RepliGut® Planar) based on human stem cells that are expanded and then differentiated to recreate the human small intestine or colonic epithelium for compound screening. ...

ByAltis Biosystems


The Problem with Gene-Modified Cell Therapy Manufacturing

The Problem with Gene-Modified Cell Therapy Manufacturing

Gene-modified cell therapies (GMCTs) represent the most effective therapeutic platform for many patients with advanced diseases including relapsed and refractory leukemia, non-Hodgkin lymphoma, and other blood cancers [1]. Specifically, chimeric antigen receptor T cell (CAR-T) therapies targeting CD19 have demonstrated remarkable responses and possibly cures in patients with advanced acute ...

ByIndee Labs


Indee Lab’s CRISPR Delivery Technology for Affordable Immunotherapies

Indee Lab’s CRISPR Delivery Technology for Affordable Immunotherapies

The mission of Indee Labs is to use microfluidic vortex shedding as a scalable method to deliver CRISPR reagents into cells for developing affordable cell and gene therapies in the future. In our previous blog post, we summarized the work from their latest publication on CRISPR-editing in T cells using microfluidic devices. In this interview, we ...

ByIndee Labs


Spectrovisc Q3000 Series Viscometer – A Portable Kinematic Oil Analysis Solution for Field-Based Users

Spectrovisc Q3000 Series Viscometer – A Portable Kinematic Oil Analysis Solution for Field-Based Users

Traditional Viscometer Theory and Design Current viscosity measurement techniques rely heavily on the use of capillary, cone and plate, and concentric cylinder viscometers. These devices are mainly limited to the laboratory setting and contain obstacles to portability. ...

ByAMETEK Spectro Scientific


Syringe Pump Applications In Bioscience & Biochemistry

Syringe Pump Applications In Bioscience & Biochemistry

Microfluidic platforms are an exciting new class of devices that integrate a multitude of biochemical techniques into a single chip, reducing experiments to a micro- or nano- scale. ...

ByChemyx Inc


Nanotechnologies dedicated to nucleation control

Nanotechnologies dedicated to nucleation control

Localisation in space with a microfluidic device produces hundreds of nanovolume crystallisers where concentration and temperature are easily monitored. ...

ByInderscience Publishers


Reversible wettability of hybrid organic/inorganic surfaces of systems upon light irradiation/storage cycles

Reversible wettability of hybrid organic/inorganic surfaces of systems upon light irradiation/storage cycles

The direct implementation of such structures into microfluidics devices is ...

ByInderscience Publishers


An instrument transfer function approach to atomic force microscopy for surface metrology

An instrument transfer function approach to atomic force microscopy for surface metrology

First, we examined the problem of merging multiple data sets for metrology of polymer-based microfluidic devices. A methodology for the design of registration markers for data alignment is proposed using a spatial frequency-domain framework to determine parameters such as fiducial marker size and pitch. ...

ByInderscience Publishers


A teaching factory for polymer microfabrication – μFac

A teaching factory for polymer microfabrication – μFac

As part of the Singapore MIT Alliance (SMA) we have established the Center for Polymer Microfabrication (CPM) with an initial focus on processes and systems related to volume production of microfluidic devices. This research has focused on topics as diverse as material processing property characterisation and simulation, tooling and equipment design and control, ...

ByInderscience Publishers


Morphology and geometry of CO2-laser machined PMMA microchannels: influence of molecular weight and number of cut passes

Morphology and geometry of CO2-laser machined PMMA microchannels: influence of molecular weight and number of cut passes

Laser micromachining has been utilised for fabricating channels in polymeric microfluidic devices. The present work focuses on a study of the influence of polymer molecular weight (Mw) on the depth and width of microchannels in polymethyl methacrylate (PMMA) that are machined using a CO2 laser. ...

ByInderscience Publishers

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