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Mitochondrial Dna Articles & Analysis

11 articles found

ß-D-glucuronidase activity triggered monitoring of fecal contamination using microbial and chemical source tracking markers at drinking water intakes

ß-D-glucuronidase activity triggered monitoring of fecal contamination using microbial and chemical source tracking markers at drinking water intakes

This study used β-D-glucuronidase activity (GLUC) with microbial source tracking (MST) markers: human, bovine, porcine mitochondrial DNA markers (mtDNA) and human-associated Bacteroidales HF183 and chemical source tracking (CST) markers including caffeine, carbamazepine, theophylline and acetaminophen, pathogens (Giardia, Cryptosporidium, adenovirus, ...

ByColiMinder by VWMS GmbH


Targeted Region Sequencing in Human Disease Studies and Clinical Care

Targeted Region Sequencing in Human Disease Studies and Clinical Care

The clinical sample types generally include fresh or frozen tissue that often yield high quality DNA and samples that often yield low quantity and/or compromised quality DNA like FFPE (formalin-fixed paraffin-embedded) tissue, decalcified FFPE tissue, bone marrow trephines, smears, and fine needle aspirates (FNA), plasma, and circulating tumor cells. Some studies ...

ByCD Genomics


Mitochondrial Proteins

Mitochondrial Proteins

Mitochondrial DNA (mtDNA) encodes only 13 mitochondrial proteins, which are transcribed and translated within the mitochondria and become important protein components of the respiratory chain complex. mtDNA also encodes 2 ribosomal RNAs and 22 transfer RNAs, which can ensure the smooth expression of the respiratory chain complex proteins it ...

ByCreative Proteomics


Protective and antioxidant role of selenium on arsenic trioxide–induced oxidative stress and genotoxicity in the fish hepatoma cell line PLHC‐1

Protective and antioxidant role of selenium on arsenic trioxide–induced oxidative stress and genotoxicity in the fish hepatoma cell line PLHC‐1

The present study was undertaken to evaluate the protective effect of selenium on arsenic trioxide (As2O3)–induced cytotoxicity, DNA damage, and apoptosis. N‐Acetylcysteine (NAC), a free radical scavenger, was used to determine the involvement of reactive oxygen species (ROS) in As2O3‐induced DNA damage and apoptosis. ...

ByJohn Wiley & Sons, Ltd.


Removal of oxidative dna damage via fen1-dependent long-patch base excision repair in human cell mitochondria

Removal of oxidative dna damage via fen1-dependent long-patch base excision repair in human cell mitochondria

Here we report that 2-deoxyribonolactone (dL), a major type of oxidized abasic site, inhibits replication by mitochondrial DNA (mtDNA) polymerase  and interferes with SP-BER by covalently trapping polymerase  during attempted dL excision. ...

ByAmerican Society for Microbiology (ASM)


Intraspecific Genetic Diversity of Undaria pinnatifida in Japan, based on the Mitochondrial cox3 Gene and the ITS1 of nrDNA

Intraspecific Genetic Diversity of Undaria pinnatifida in Japan, based on the Mitochondrial cox3 Gene and the ITS1 of nrDNA

The intraspecific genetic diversity of the kelp Undaria pinnatifida (Harvey) Suringar (Laminariales, Phaeophyceae) was investigated using DNA sequences of the mitochondrial cytochrome oxidase subunit 3 (cox3) gene and internal transcribed spacer 1 (ITS1) of nuclear ribosomal DNA in plants collected from 21 localities along the Japanese coast ...

BySpringer-Verlag GmbH


Phylogenetics, population structure and genetic diversity of the endangered southern brown bandicoot (Isoodon obesulus) in south-eastern Australia

Phylogenetics, population structure and genetic diversity of the endangered southern brown bandicoot (Isoodon obesulus) in south-eastern Australia

This species currently has a highly fragmented distribution inhabiting a mosaic of habitats. This project uses mitochondrial DNA (mtDNA) and microsatellite data to determine levels of genetic diversity, population structure and evolutionary history, which can aid wildlife managers in setting priorities and determining management strategies. ...

BySpringer-Verlag GmbH


Polymorphism in Nucleotide Sequence of Mitochondrial Intergenic Region in Scleractinian Coral (Galaxea fascicularis)

Polymorphism in Nucleotide Sequence of Mitochondrial Intergenic Region in Scleractinian Coral (Galaxea fascicularis)

A region of 826 bp that is unlikely to code for a protein, ribosomal RNA, or transfer RNA was identified between the cytochrome b and NADH–ubiquinone oxidoreductase chain 2 loci in the mitochondrial DNA of the scleractinian reef coral Galaxea fascicularis. Nucleotide sequences were determined in a part (625 bp) of this intergenic region in 95 individuals ...

BySpringer-Verlag GmbH


Mitochondrial DNA variation in the European lobster ( Homarus gammarus) throughout the range

Mitochondrial DNA variation in the European lobster ( Homarus gammarus) throughout the range

The genetic differentiation of the European lobster (Homarus gammarus) was investigated in 3,283 individuals from 44 population samples throughout its geographical distribution (Norway to Greece) by means of polymerase chain reaction restriction fragment length polymorphism analysis of a 3-kb mitochondrial DNA segment. Ninety composite haplotypes were revealed ...

BySpringer-Verlag GmbH


Mitochondrial evolution and phylogeography in the hydrozoan Obelia geniculata (Cnidaria)

Mitochondrial evolution and phylogeography in the hydrozoan Obelia geniculata (Cnidaria)

The distribution and genetic structure of many marine invertebrates in the North Atlantic have been influenced by the Pleistocene glaciation, which caused local extinctions followed by recolonization in warmer periods. Mitochondrial DNA markers are typically used to reconstruct species histories. Here, two mitochondrial markers [16S rDNA and ...

BySpringer-Verlag GmbH


Molecular genetic variation in tarpon ( Megalops atlanticus Valenciennes) in the northern Atlantic Ocean

Molecular genetic variation in tarpon ( Megalops atlanticus Valenciennes) in the northern Atlantic Ocean

In this study we used two molecular genetic techniques—protein electrophoresis of nuclear DNA loci, and restriction fragment length polymorphism analysis of the mitochondrial DNA (mtDNA)—to assess this species population genetic structure in the eastern (coastal waters off Gabon and Sierra Leone, Africa) and western (coastal waters off Florida, ...

BySpringer-Verlag GmbH

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