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Nanoparticle Articles & Analysis
871 articles found
Lipid nanoparticles (LNPs) occupy a central role in the development of innovative nucleic acid–based therapies. ...
"Our functionalized DSPE-PEG derivatives provide the structural uniformity required to build stable liposomes and polymer nanoparticles. This reliability ensures that target ligands attach precisely and that sensitive therapeutic payloads remain protected until they reach their destination," said a Senior Scientist at Biopharma PEG. ...
They are commonly applied in lipid nanoparticles, ADCs, PROTACs, polymer-drug conjugates, click chemistry, and surface modification. ...
This study develops a biodegradable photocatalytic membrane with titanium dioxide (TiO2, p25) nanoparticles with a polylactic acid (PLA) support to remove volatile organic compounds (VOCs) from indoor air. ...
The therapy uses targeted lipid nanoparticles (tLNPs) to deliver CAR-encoding mRNA directly to immune cells. ...
For most of human history, the materials behind great artifacts were a matter of educated guesswork. Was that dagger really made from a fallen star? How did a Roman glass cup change color from green to red? What alloys did ancient mints and silversmiths actually use? X-ray fluorescence (XRF) has quietly become one of the main tools for answering these questions. It lets scientists determine what ...
Therefore, the remediation company DEKONTA arrived at an inventive decision to combine the direct-push injected NANOFER particles with a subsequent employment of the thermally enhanced in-situ bioremediation supported by the application of organic substrate (lactate). REMEDIATION APPROACH Iron nanoparticles were applied under pressure into a very complex geological matrix in ...
This study rigorously investigated the effect of charge-enhanced dry impregnation (CEDI) method on the physicochemical properties and catalytic performance of a ceria-supported nickel-based catalyst. The primary objective of the CEDI method was to augment the electrostatic adsorption of the nickel precursor onto the ceria support surface during the dry impregnation (DI) process. For a ...
This precision benefits ADC and linker development by providing: l Consistent linker-to-antibody ratios l Reliable pharmacokinetic profiles l Reduced batch-to-batch variation l Improved reaction predictability in conjugation workflows Broader Applications in Bioconjugation Monodispersed azide-PEGs have found wide applications beyond ADCs, including: l Nanoparticle and liposome ...
Nanomaterial engineering is rapidly becoming a common technique for improving optical detection in various applications. Nanoparticles possess unique chemical and physical properties, offering important possibilities as probes in biological analysis. ...
With the development of nanotechnology, a variety of nanodrug delivery systems (NDDS) have been designed and prepared, such as the most familiar liposomes, polymer nanoparticles, and metal nanoparticles. However, a new kind of drug delivery system has also gradually emerged in recent years: lipid nanodiscs (LNDs). ...
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. Current therapies for IPF rely on oral administration of pirfenidone and nintedanib, two FDA-approved drugs that slow disease progression. While ...
Fluorescently labeled polysaccharide nanoparticles stored at over 80% humidity and 37°C lost 30% of their fluorescence within a week, due to polymer hydrolysis and label detachment. l In vivo stability: Once inside a living organism, these biopolymers degrade quickly. ...
ByMatexcel
Virus-like particles (VLPs) have garnered significant attention in recent years for their potential applications in vaccine development, drug delivery, and as tools in various biotechnological fields. These nanoparticles mimic the structure of viruses but lack the viral genetic material that makes viruses infectious. ...
Understanding Nanocomposite Coatings Nanocomposite coatings consist of nanoparticles embedded in a matrix material. They offer exceptional strength and wear resistance. ...
Researchers have prepared fluorescent polystyrene nanoparticles of different sizes and applied them in fluorescence analysis. ...
Microfluidic techniques show promise in producing liposomes and nanoparticles for drug delivery applications, as they can generate uniform formulations with controlled properties. ...
Whether it is medical research or drug manufacturing, tablet press is a vital link. Let's see how to choose the one that suits you best.Grand pack.The field of drug delivery is constantly evolving, driven by the core goal of improving therapeutic outcomes—enhancing efficacy, reducing toxicity, boosting patient compliance, and even enabling entirely new medical treatments. The global drug delivery ...
Since its first FDA-approved application in 1990 with Adagen® (pegademase bovine), PEGylation has been widely adopted in biopharmaceuticals, including proteins, peptides, antibodies, and nanoparticles. This article explores the mechanisms, benefits, challenges, and future prospects of PEGylation in drug development. ...
These technologies could pave the way for more personalized therapies, where recombinant chemokines or inhibitors are tailored to a patient’s unique chemokine signature. Furthermore, nanoparticle delivery systems are being explored to enhance the stability and targeted delivery of recombinant chemokines. ...