Neuroendocrine Articles & Analysis
10 articles found
DLL3 plays a critical role in neurogenesis and is also implicated in various cancers, particularly in the development of neuroendocrine tumors. The ability to study DLL3 in a stable cell line allows researchers to elucidate its functions and interactions within the signaling pathways more comprehensively. ...
Models of several cancer types, such as gastric, breast or neuroendocrine cancers, have been developed using this technique. Due to all the previously described advantages presented by the zebrafish animal model, it has recently come to the fore in the drug discovery process (i) to identify molecules that specifically ameliorate disease phenotypes and (ii) to conduct detailed ...
In 2016, [18F]FET-βAG-TOCA was first used in clinical trials for neuroendocrine tumor patients. Recently, [68Ga]Ga-Trivehexin, synthesized via CuAAC, was used for PET-CT imaging in patients with pancreatic ductal adenocarcinoma. ...
The core programs include: Octreotide for acromegaly or neuroendocrine tumors in the GI tract. Acromegaly is a hormonal disorder that develops when the pituitary gland produces too much growth hormone during adulthood. ...
They include: Octreotide for acromegaly or neuroendocrine tumors in the GI tract (NETs) TNF-alpha inhibitors for psoriatic arthritis Parathyroid hormone (PTH) for osteoporosis Human growth hormone (HGH) for HGH deficiency Parathyroid hormone for hypothyroidism The product furthest along in the research cycle is the pill developed to administer octreotide (called ...
Rani Therapeutics is a clinical-stage biotherapeutics company offering an alternative to painful injections for patients with chronic conditions such as neuroendocrine tumours(NETS). The company based in San Jose, California debuted on the Nasdaq last week in its first initial public offering. ...
RT-101 is being evaluated for acromegaly, and Rani expects to run trials for neuroendocrine tumor of the gastrointestinal tract as well as carcinoid syndrome, the CEO said. ...
We highlight studies on the effects of antidepressants, on particularly crustacean and molluscan groups showing they are susceptible to a wide variety of neuroendocrine disruption at environmentally relevant concentrations (pg‐ng/L). ...
Gamma‐aminobutyric acid (GABA) and GABA receptors play an important role in neuroendocrine regulation in fish. Disruption of the GABAergic system by environmental contaminants could interfere with normal regulation of the hypothalamic‐pituitary‐gonadal axis, leading to impaired fish reproduction. ...
The low background in the abdominal region is favourable for the diagnosis of neuroendocrine tumours.Keywords: octreotide, somatostatin, technetium-99m, neuroendocrine tumours, tumour diagnosis, Swiss mice, radiochemicals, blood clearance, labelled peptides, kidney uptake, urinary ...