Neurology Function Articles & Analysis
8 articles found
Rett syndrome (RTT) is a severe neurodevelopmental disorder caused by mutations in the MECP2 gene, leading to various symptoms, including cognitive impairment, motor dysfunction, and significant respiratory abnormalities. These respiratory issues, such as apneas and irregular breathing patterns, are not only hallmark symptoms of RTT but also serve as critical indicators of disease progression ...
Introduction By leveraging Connectomics to trace functional connectivity, seven large-scale brain networks have been identified. These networks have the most dominance over cortical function in the brain, and each serves an overarching common function. While some networks are familiar, many networks, and their constituents, are newly discovered1. These major networks control brain ...
COPII mediates the transport of membrane proteins and soluble proteins from the endoplasmic reticulum to the Golgi apparatus, and abnormal function of COPII inhibits protein secretion and has effects on cell differentiation and homeostasis, and many studies have shown a link between COPII components and human diseases, such as Sec31 mutations leading to severe ...
This specificity determines their involvement in specific functions, such as cell growth or neuronal function, and consequently in related diseases, such as cancer or neurodegenerative diseases, such as Alzheimer's disease. ...
I have been through 40+ years of debate and discovery around mechanical, fascial, postural, functional, movement-based, neurological and psychological models of assessment and treatment, all of which claim not only to address what ails the dysfunctional, painful body, but to be THE ANSWER. ...
Such wearable sensing technologies could be used outside of the clinic to monitor “homework,” as task practice outside of structured therapy sessions can improve neurological recovery and functional abilities (Dobkin, 2004; Harris et al., 2009). ...
While potentially beneficial in ischemia, upregulation of the HIF1 transcription factor has been linked to inflammation, poor prognosis in many cancers, and decreased susceptibility of tumors to radiotherapy and chemotherapy. Considering HIF1's function, HIF1 protein and its hydroxylation cofactors look increasingly attractive as therapeutic targets. Independently, antioxidants ...
While potentially beneficial in ischemia, upregulation of the HIF1 transcription factor has been linked to inflammation, poor prognosis in many cancers, and decreased susceptibility of tumors to radiotherapy and chemotherapy. Considering HIF1's function, HIF1 protein and its hydroxylation cofactors look increasingly attractive as therapeutic targets. Independently, antioxidants ...