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Phenotype Analysis Articles & Analysis
15 articles found
With advanced tools and diverse methodologies, Lifeasible is empowering agricultural researchers, plant breeders, and conservation biologists to gain deeper insights into genetic diversity, facilitating breakthroughs in crop improvement, biodiversity conservation, and trait analysis. The ability to detect genetic variation among plant germplasm is essential for crop improvement ...
The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. ...
So far, some biotech giants have established a series of research and development technologies for genetically modified animal models, such as gene cloning, gene knockout plasmid construction, experimental animal embryonic stem cell manipulation, strain breeding, and phenotype analysis. Combined with these technologies, there would be more stable and reliable ...
AdvaitaBio’s IPathwayGuide plays significant role in the research of a Stanford investigator. Stanford University is one of the world’s leading research and teaching institutions. With a 1.69 billion dollar annual sponsored research budget, Stanford has been delivering breakthrough discoveries in numerous domains. For over 6 years, Dr. Linda Yip has been conducting research at ...
My previous post, Pathway Analysis vs Gene Set Analysis, ended with an interesting question: has anybody really compared side-by-side gene set analysis methods and pathway analysis methods on the same data sets? ...
The paper tackles 2 important problems: 1) analysis of complex single cell datasets; 2) prediction of response to immunotherapy in cancer. ...
Gene panels make NGS and data analysis more economical, flexible and efficient. The use of them can improve the detection of genetically heterogeneous disorders and diseases with overlapping phenotypes, while assessing multiple potential genetic causes of suspicion. ...
Congratulations are in order as the University of Birmingham is the most recent university to expand the footprint of metabolic phenotyping research centres around the world. As state-of-the-art metabolic phenotyping facilities able to conduct small-scale and large-scale studies in medical research and stratified medicine, the Phenome Centre Birmingham joins the ...
Abstract The heritability of coronary atherosclerotic plaque burden, coronary geometry, and phenotypes associated with increased cardiometabolic risk are largely unknown. ...
The study is analyzed in 3 subsequent phases, and each phase consists of a discovery cohort and an independent validation cohort. For the primary analysis, the primary phenotype will be the presence of any atherosclerotic plaque, as detected by cardiac CT. Additional phenotypic analyses will include per patient maximal luminal stenosis defined as ...
The isolate, designated strain KM2, was assigned to the genus Marinobacter based on a variety of phenotypic properties and by analysis of the 16S rRNA gene sequence. The isolate displays an absolute growth requirement for NaCl which cannot be offset by replacement of NaCl with other salts. ...
A retrospective analysis of coliform events in a drinking water distribution system was conducted. A total of 13 coliform isolates with specific geographic/sampling records were analysed using microbial source tracking (MST) to establish genetic (based on DNA) and phenotypic (based on substrate utilization) relatedness between isolates, and a data integration ...
The core collection was evaluated for 11 qualitative and 10 quantitative traits in an augmented design using three control cultivars in the 2004–2005 post-rainy season. The hierarchical cluster analysis of data using phenotypic distances resulted in 21 clusters. From each cluster, about 10% or a minimum of one accession was selected to form a mini core that ...
Development of core collections is an effective tool to extensively characterize large germplasm collections, and the use of a mini-core subsampling strategy further increases the effectiveness of genetic diversity analysis at detailed phenotype and molecular levels. We report the formation of a mini-core subset containing 217 entries derived from 1794 core ...
NAG1 encodes a 19-kDa protein, detected by Western blotting of hemagglutinin (HA)-tagged Nag1p with anti-HA antibodies and by β-galactosidase analysis of a NAG1-lacZ fusion. NAG1 is evolutionarily conserved as a unit with YGR031W in bacteria and fungi. Unlike the YGR031WP protein product, however, which localizes to the mitochondria, Nag1p localizes to the cell periphery, ...